ID   FLOA_FINM2              Reviewed;         327 AA.
AC   B0S1F0;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Flotillin-like protein FloA {ECO:0000255|HAMAP-Rule:MF_01562};
GN   Name=floA {ECO:0000255|HAMAP-Rule:MF_01562}; OrderedLocusNames=FMG_0772;
OS   Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508)
OS   (Peptostreptococcus magnus).
OC   Bacteria; Firmicutes; Tissierellia; Tissierellales; Peptoniphilaceae;
OC   Finegoldia.
OX   NCBI_TaxID=334413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29328 / DSM 20472 / WAL 2508;
RX   PubMed=18263572; DOI=10.1093/dnares/dsm030;
RA   Goto T., Yamashita A., Hirakawa H., Matsutani M., Todo K., Ohshima K.,
RA   Toh H., Miyamoto K., Kuhara S., Hattori M., Shimizu T., Akimoto S.;
RT   "Complete genome sequence of Finegoldia magna, an anaerobic opportunistic
RT   pathogen.";
RL   DNA Res. 15:39-47(2008).
CC   -!- FUNCTION: Found in functional membrane microdomains (FMM) that may be
CC       equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and
CC       increase in number as cells age. Flotillins are thought to be important
CC       factors in membrane fluidity. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBUNIT: Homooligomerizes. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01562};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC       Membrane raft {ECO:0000255|HAMAP-Rule:MF_01562}; Single-pass membrane
CC       protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SIMILARITY: Belongs to the flotillin-like FloA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01562}.
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DR   EMBL; AP008971; BAG08190.1; -; Genomic_DNA.
DR   RefSeq; WP_002836436.1; NC_010376.1.
DR   AlphaFoldDB; B0S1F0; -.
DR   SMR; B0S1F0; -.
DR   STRING; 334413.FMG_0772; -.
DR   PRIDE; B0S1F0; -.
DR   EnsemblBacteria; BAG08190; BAG08190; FMG_0772.
DR   GeneID; 60840174; -.
DR   KEGG; fma:FMG_0772; -.
DR   eggNOG; COG4864; Bacteria.
DR   HOGENOM; CLU_836378_0_0_9; -.
DR   OMA; GIMDYYR; -.
DR   OrthoDB; 827327at2; -.
DR   Proteomes; UP000001319; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01562; FloA; 1.
DR   InterPro; IPR022853; FloA.
DR   Pfam; PF12127; YdfA_immunity; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..327
FT                   /note="Flotillin-like protein FloA"
FT                   /id="PRO_1000199715"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01562"
SQ   SEQUENCE   327 AA;  35220 MW;  0B2C556A3BEF58D1 CRC64;
     MPFEIPFLVP ILIVILLLVF FSLVPVGLWV TAQFSGVHVK ISQLIGMRLR RVIPKNIINP
     LIKATKAGLN LTTNQLEAHY LAGGNVNTLV NALIAAQRAD IELEFERAAA IDLAGRNVLE
     AVQVSVNPKV IETPNIAAVA MNGIEVIVKA KVTVRANIER LIGGAGEETI IARVGEGIVT
     TVGSSESHTS VLENPDSISK TVLNKGLDSG TAFEILSIDI ADVDVGRNIG AKLQTDQAEA
     DKRIAQAKAE ERRAMAVAKE QEMIAEVRSM RAKVVESESK VPLAIAKALE SGNLGVLDYY
     NMKNIISDTE MRQAISGNSE KIKEDDK