位置:首页 > 蛋白库 > FLOA_PHOV8
FLOA_PHOV8
ID   FLOA_PHOV8              Reviewed;         332 AA.
AC   A6L6E5;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Flotillin-like protein FloA {ECO:0000255|HAMAP-Rule:MF_01562};
GN   Name=floA {ECO:0000255|HAMAP-Rule:MF_01562}; OrderedLocusNames=BVU_3648;
OS   Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 /
OS   NBRC 14291 / NCTC 11154) (Bacteroides vulgatus).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Phocaeicola.
OX   NCBI_TaxID=435590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC
RC   11154;
RX   PubMed=17579514; DOI=10.1371/journal.pbio.0050156;
RA   Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C.,
RA   Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H.,
RA   Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K.,
RA   Knight R.D., Gordon J.I.;
RT   "Evolution of symbiotic bacteria in the distal human intestine.";
RL   PLoS Biol. 5:1574-1586(2007).
CC   -!- FUNCTION: Found in functional membrane microdomains (FMM) that may be
CC       equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and
CC       increase in number as cells age. Flotillins are thought to be important
CC       factors in membrane fluidity. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBUNIT: Homooligomerizes. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01562};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC       Membrane raft {ECO:0000255|HAMAP-Rule:MF_01562}; Single-pass membrane
CC       protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SIMILARITY: Belongs to the flotillin-like FloA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000139; ABR41259.1; -; Genomic_DNA.
DR   RefSeq; WP_005839405.1; NC_009614.1.
DR   AlphaFoldDB; A6L6E5; -.
DR   SMR; A6L6E5; -.
DR   STRING; 435590.BVU_3648; -.
DR   DNASU; 5304607; -.
DR   EnsemblBacteria; ABR41259; ABR41259; BVU_3648.
DR   GeneID; 56617923; -.
DR   GeneID; 66749473; -.
DR   KEGG; bvu:BVU_3648; -.
DR   eggNOG; COG4864; Bacteria.
DR   HOGENOM; CLU_836378_0_0_10; -.
DR   OMA; GIMDYYR; -.
DR   Proteomes; UP000002861; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01562; FloA; 1.
DR   InterPro; IPR022853; FloA.
DR   Pfam; PF12127; YdfA_immunity; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..332
FT                   /note="Flotillin-like protein FloA"
FT                   /id="PRO_1000069041"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01562"
SQ   SEQUENCE   332 AA;  35991 MW;  54526974371400E4 CRC64;
     MIEPNYLPFI LIGGGIIFVV LFFHYVPFFL WLSAKVSGVR ISLVQLFLMR IRNVPPYVIV
     PAMIEAHKAG LSNITRDELE AHYMAGGHVE KVVHALVSAS KANIELSFQM ATGIDLAGRD
     VFEAVQMSVN PKVIDTPPVT AVAKDGIQLI AKARVTVRAN IRQLVGGAGE DTILARVGEG
     IVSSIGSSEN HKSVLENPDS ISKLVLRKGL DAGTAFEILS IDIADIDIGR NIGAALQIDQ
     ANADKNIAQA KAEERRAMAV ALEQEMKAKA EEARANVIQA EAEVPKAMAE AFRSGNLGIM
     DYYRMKNIQA DTSMRENIAK PETTFGNEPL SK
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024