FLOT1_ORYSJ
ID FLOT1_ORYSJ Reviewed; 485 AA.
AC Q9AV57; A0A0P0XW05;
DT 13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Flotillin-like protein 1;
DE AltName: Full=Nodulin-like protein 1;
GN Name=FLOT1; OrderedLocusNames=Os10g0481500, LOC_Os10g34040;
GN ORFNames=OsJ_31920, OSJNBa0012L23.36, OSJNBa0093B11.7;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12791992; DOI=10.1126/science.1083523;
RA Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: May act as a scaffolding protein within caveolar membranes,
CC functionally participating in formation of caveolae or caveolae-like
CC vesicles. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}. Membrane, caveola {ECO:0000250}.
CC -!- PTM: May be palmitoylated. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the band 7/mec-2 family. Flotillin subfamily.
CC {ECO:0000305}.
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DR EMBL; AC024594; AAK21341.1; -; Genomic_DNA.
DR EMBL; AC051632; AAM91865.1; -; Genomic_DNA.
DR EMBL; DP000086; AAP54307.1; -; Genomic_DNA.
DR EMBL; AP008216; BAF26794.1; -; Genomic_DNA.
DR EMBL; AP014966; BAT11345.1; -; Genomic_DNA.
DR EMBL; CM000147; EAZ16450.1; -; Genomic_DNA.
DR RefSeq; XP_015613363.1; XM_015757877.1.
DR AlphaFoldDB; Q9AV57; -.
DR STRING; 4530.OS10T0481500-00; -.
DR PaxDb; Q9AV57; -.
DR PRIDE; Q9AV57; -.
DR EnsemblPlants; Os10t0481500-00; Os10t0481500-00; Os10g0481500.
DR GeneID; 4348926; -.
DR Gramene; Os10t0481500-00; Os10t0481500-00; Os10g0481500.
DR KEGG; osa:4348926; -.
DR eggNOG; KOG2668; Eukaryota.
DR HOGENOM; CLU_030844_1_1_1; -.
DR InParanoid; Q9AV57; -.
DR OMA; QPKINVW; -.
DR OrthoDB; 812555at2759; -.
DR Proteomes; UP000000763; Chromosome 10.
DR Proteomes; UP000007752; Chromosome 10.
DR Proteomes; UP000059680; Chromosome 10.
DR Genevisible; Q9AV57; OS.
DR GO; GO:0005901; C:caveola; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0044853; C:plasma membrane raft; IBA:GO_Central.
DR GO; GO:0072659; P:protein localization to plasma membrane; IBA:GO_Central.
DR Gene3D; 3.30.479.30; -; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR027705; Flotillin_fam.
DR PANTHER; PTHR13806; PTHR13806; 1.
DR Pfam; PF01145; Band_7; 1.
DR SUPFAM; SSF117892; SSF117892; 1.
PE 3: Inferred from homology;
KW Cell membrane; Coiled coil; Lipoprotein; Membrane; Palmitate;
KW Reference proteome.
FT CHAIN 1..485
FT /note="Flotillin-like protein 1"
FT /id="PRO_0000395212"
FT COILED 228..320
FT /evidence="ECO:0000255"
FT LIPID 38
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 485 AA; 52987 MW; A52FB4D0343FA5DC CRC64;
MGFAYRIASA SEYLAITGYG IADVKLAKKA WVAPGQRCTR FDISPVNYTF EVQAMSAEKL
PFILPAVFTI GPRADDDDCL LRYAKLISPH DKLSHHVNEL VKGVIEGETR VLAASMTMEE
IFQGTKSFKQ AVFENVQLEL NQFGLIIYNA NVKQLVDVAG HEYFSYLGQK TQQEAVNQAK
VDVAEARMKG EVGAKERDGM TRQNAAKVDA ETKVYTVKRQ GEGAKEEARV KAEVKVFENE
REAEVAEANA DLAMKKAGWQ RQAMVAEVEA AKAVAIREAE LQVEVERTNA SRQTEKLKAE
HLSKAVVDYE MKVQEANWEL YNRQKAAEAL LYEQEKQAEA RRASADAAFF ARQREAEAEL
YAKQKEAEGL VAMGDAQSAY LSAMLGALGG SYAALRDYLM VSSGVYQEMA RINADAIRGL
EPKISVWSNG AGAGGEVGEG GGAMKEVAGV YKMLPPLLTT VHEQTGMLPP AWMGTLTGGA
PSSTS
