ID   FLO_ANTMA               Reviewed;         396 AA.
AC   P23915;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Floricaula protein;
GN   Name=FLO;
OS   Antirrhinum majus (Garden snapdragon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Plantaginaceae; Antirrhineae; Antirrhinum.
OX   NCBI_TaxID=4151;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
RX   PubMed=1702033; DOI=10.1016/0092-8674(90)90426-f;
RA   Coen E.S., Romero J.M., Doyle S., Elliott R., Murphy G., Carpenter R.;
RT   "Floricaula: a homeotic gene required for flower development in Antirrhinum
RT   majus.";
RL   Cell 63:1311-1322(1990).
CC   -!- FUNCTION: Required for flower development. FLO may interact in a
CC       sequential manner with other homeotic genes affecting floral organ
CC       identity.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=P23915-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=P23915-2; Sequence=VSP_001562;
CC   -!- TISSUE SPECIFICITY: Bract, sepal, petal, and carpel primordia, but not
CC       in stamen primordia.
CC   -!- DEVELOPMENTAL STAGE: Transiently expressed in the very early stages of
CC       flower development.
CC   -!- SIMILARITY: Belongs to the FLO/LFY family. {ECO:0000305}.
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DR   EMBL; M55525; AAA62574.1; -; mRNA.
DR   PIR; A36339; A36339.
DR   AlphaFoldDB; P23915; -.
DR   SMR; P23915; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.4180.10; -; 1.
DR   InterPro; IPR035209; FLO/LFY_C.
DR   InterPro; IPR002910; FLO_LFY.
DR   InterPro; IPR038276; Floricaula/leafy_C_sf.
DR   InterPro; IPR035079; LFY_SAM.
DR   PANTHER; PTHR36079; PTHR36079; 1.
DR   Pfam; PF17538; C_LFY_FLO; 1.
DR   Pfam; PF01698; SAM_LFY; 1.
PE   2: Evidence at transcript level;
KW   Activator; Alternative splicing; Developmental protein; Differentiation;
KW   DNA-binding; Flowering; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..396
FT                   /note="Floricaula protein"
FT                   /id="PRO_0000129146"
FT   DNA_BIND        221..225
FT                   /evidence="ECO:0000250"
FT   DNA_BIND        290..297
FT                   /evidence="ECO:0000250"
FT   DNA_BIND        361..364
FT                   /evidence="ECO:0000250"
FT   REGION          144..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..212
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            268
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250"
FT   SITE            275
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250"
FT   SITE            279
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250"
FT   SITE            326
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250"
FT   VAR_SEQ         143
FT                   /note="E -> EV (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:1702033"
FT                   /id="VSP_001562"
SQ   SEQUENCE   396 AA;  44790 MW;  80954DCFE91739A7 CRC64;
     MDPDAFLFKW DHRTALPQPN RLLDAVAPPP PPPPQAPSYS MRPRELGGLE ELFQAYGIRY
     YTAAKIAELG FTVNTLLDMR DEELDEMMNS LCQIFRWDLL VGERYGIKAA VRAERRRIDE
     EEVRRRHLLL GDTTHALDAL SQEGLSEEPV QQEKEAMGSG GGGVGGVWEM MGAGGRKAPQ
     RRRKNYKGRS RMASMEEDDD DDDDETEGAE DDENIVSERQ REHPFIVTEP GEVARGKKNG
     LDYLFHLYEQ CRDFLIQVQT IAKERGEKCP TKVTNQVFRY AKKAGANYIN KPKMRHYVHC
     YALHCLDEAA SNALRRAFKE RGENVGAWRQ ACYKPLVAIA ARQGWDIDTI FNAHPRLSIW
     YVPTKLRQLC HAERSSAAVA ATSSITGGGP ADHLPF