ID   FLQE2_MYCTO             Reviewed;         252 AA.
AC   P9WJB2; I1SB22; O07188; Q7D6S1;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Fluoroquinolones export permease protein MT2760;
GN   OrderedLocusNames=MT2760;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Part of the ABC transporter complex involved in
CC       fluoroquinolones export. Probably responsible for the translocation of
CC       the substrate across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of 2 ATP-binding proteins and 2
CC       transmembrane proteins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000516; AAK47075.1; -; Genomic_DNA.
DR   PIR; A70529; A70529.
DR   RefSeq; WP_003413897.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJB2; -.
DR   SMR; P9WJB2; -.
DR   EnsemblBacteria; AAK47075; AAK47075; MT2760.
DR   KEGG; mtc:MT2760; -.
DR   PATRIC; fig|83331.31.peg.2972; -.
DR   HOGENOM; CLU_098655_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antibiotic resistance; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..252
FT                   /note="Fluoroquinolones export permease protein MT2760"
FT                   /id="PRO_0000427860"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   252 AA;  27144 MW;  D2C40E38626B58F7 CRC64;
     MRAISSLAGP RALAAFGRND IRGTYRDPLL VMLVIAPVIW TTGVALLTPL FTEMLARRYG
     FDLVGYYPLI LTAFLLLTSI IVAGALAAFL VLDDVDAGTM TALRVTPVPL SVFFGYRAAT
     VMVVTTIYVV ATMSCSGILE PGLVSSLIPI GLVAGLSAVV TLLLILAVAN NKIQGLAMVR
     ALGMLIAGLP CLPWFISSNW NLAFGVLPPY WAAKAFWVAS DHGTWWPYLV GGAVYNLAIV
     WVLFRRFRAK HA