ID   FLQE3_MYCTO             Reviewed;         237 AA.
AC   P9WJB0; L0TAC5; O07189; Q7D6S0;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Fluoroquinolones export permease protein MT2761;
GN   OrderedLocusNames=MT2761;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Part of the ABC transporter complex involved in
CC       fluoroquinolones export. Probably responsible for the translocation of
CC       the substrate across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of 2 ATP-binding proteins and 2
CC       transmembrane proteins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000516; AAK47076.1; -; Genomic_DNA.
DR   PIR; B70529; B70529.
DR   RefSeq; WP_003413912.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJB0; -.
DR   EnsemblBacteria; AAK47076; AAK47076; MT2761.
DR   KEGG; mtc:MT2761; -.
DR   PATRIC; fig|83331.31.peg.2973; -.
DR   HOGENOM; CLU_099729_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antibiotic resistance; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..237
FT                   /note="Fluoroquinolones export permease protein MT2761"
FT                   /id="PRO_0000427861"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   237 AA;  25576 MW;  9A240CD234B4631E CRC64;
     MTRLVPALRL ELTLQVRQKF LHAAVFSGLI WLAVLLPMPV SLRPVAEPYV LVGDIAIIGF
     FFVGGTVFFE KQERTIGAIV STPLRFWEYL AAKLTVLLAI SLFVAVVVAT IVHGLGYHLL
     PLVAGIVLGT LLMLLVGFSS SLPFASVTDW FLAAVIPLAI MLAPPVVHYS GLWPNPVLYL
     IPTQGPLLLL GAAFDQVSLA PWQVGYAVVY PIVCAAGLCR AAKALFGRYV VQRSGVL