ID   FLR_MEGG1               Reviewed;         194 AA.
AC   Q9KIT1;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Flavoredoxin;
GN   Name=flr;
OS   Megalodesulfovibrio gigas (strain ATCC 19364 / DSM 1382 / NCIMB 9332 / VKM
OS   B-1759) (Desulfovibrio gigas).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Megalodesulfovibrio.
OX   NCBI_TaxID=1121448;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 19364 / DSM 1382 / NCIMB 9332 / VKM B-1759;
RX   PubMed=10860809; DOI=10.1006/bbrc.2000.2834;
RA   Agostinho M., Oliveira S., Broco M., Liu M.-Y., LeGall J.,
RA   Rodrigues-Pousada C.;
RT   "Molecular cloning of the gene encoding flavoredoxin, a flavoprotein from
RT   Desulfovibrio gigas.";
RL   Biochem. Biophys. Res. Commun. 272:653-656(2000).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-38, SUBUNIT, AND COFACTOR.
RC   STRAIN=ATCC 19364 / DSM 1382 / NCIMB 9332 / VKM B-1759;
RX   PubMed=8387752; DOI=10.1006/abbi.1993.1253;
RA   Chen L., Liu M.-Y., LeGall J.;
RT   "Isolation and characterization of flavoredoxin, a new flavoprotein that
RT   permits in vitro reconstitution of an electron transfer chain from
RT   molecular hydrogen to sulfite reduction in the bacterium Desulfovibrio
RT   gigas.";
RL   Arch. Biochem. Biophys. 303:44-50(1993).
CC   -!- FUNCTION: Participates in the reduction of hydrogensulfite from
CC       hydrogen.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000269|PubMed:8387752};
CC       Note=Binds 1 FMN per subunit. {ECO:0000269|PubMed:8387752};
CC   -!- SUBUNIT: Homodimer. {ECO:0000269|PubMed:8387752}.
CC   -!- SIMILARITY: Belongs to the flavoredoxin family. {ECO:0000305}.
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DR   EMBL; AF225976; AAF82037.1; -; Genomic_DNA.
DR   PIR; JC7292; JC7292.
DR   RefSeq; WP_021758541.1; NZ_AUBO01000035.1.
DR   AlphaFoldDB; Q9KIT1; -.
DR   SMR; Q9KIT1; -.
DR   STRING; 1121448.DGI_0046; -.
DR   OMA; YVAEFPL; -.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016646; F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR   Gene3D; 2.30.110.10; -; 1.
DR   InterPro; IPR002563; Flavin_Rdtase-like_dom.
DR   InterPro; IPR012349; Split_barrel_FMN-bd.
DR   Pfam; PF01613; Flavin_Reduct; 1.
DR   SMART; SM00903; Flavin_Reduct; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Flavoprotein; FMN.
FT   CHAIN           1..194
FT                   /note="Flavoredoxin"
FT                   /id="PRO_0000085520"
SQ   SEQUENCE   194 AA;  21054 MW;  A06711DEDB5B3C11 CRC64;
     MKRSLGAKPL LFPTPVLVVG TYDDQGRPNA MTAAWGGICC SKPPCVTVSL RKATYTYASL
     MARKAYTLHV TDEPHLTASD FLGMASGRDG DKLGTLGLTT VRSELVDAPI IQEYPLVLEC
     KIVHVHDLGL HTMFVGEVQD IKADARVLDE KGHLLLDALK PLGFMPEVRT YHGMGPALGR
     AFDAGKLHMP KKAE