ID   FLTOP_CHLRE             Reviewed;         137 AA.
AC   A8IVJ1;
DT   04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Protein Flattop homolog {ECO:0000305};
DE   AltName: Full=Cilia- and flagella-associated protein 126 {ECO:0000250|UniProtKB:Q6P8X9};
DE   AltName: Full=Flagellum-associated protein 126 {ECO:0000305};
GN   Name=CFAP126 {ECO:0000250|UniProtKB:Q6P8X9};
GN   Synonyms=FAP126 {ECO:0000312|EMBL:EDP03452.1},
GN   FLTP {ECO:0000250|UniProtKB:Q6P8X9};
GN   ORFNames=CHLREDRAFT_190291 {ECO:0000312|EMBL:EDP03452.1};
OS   Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX   NCBI_TaxID=3055;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC-503;
RX   PubMed=17932292; DOI=10.1126/science.1143609;
RA   Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA   Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA   Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA   Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA   Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA   Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA   Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA   Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA   Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA   Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA   Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA   Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA   Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA   Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA   Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA   Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA   Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA   Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA   Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA   Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA   Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT   "The Chlamydomonas genome reveals the evolution of key animal and plant
RT   functions.";
RL   Science 318:245-250(2007).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=15998802; DOI=10.1083/jcb.200504008;
RA   Pazour G.J., Agrin N., Leszyk J., Witman G.B.;
RT   "Proteomic analysis of a eukaryotic cilium.";
RL   J. Cell Biol. 170:103-113(2005).
CC   -!- FUNCTION: May act as a regulator of cilium basal body docking and
CC       positioning in mono- and multiciliated cells.
CC       {ECO:0000250|UniProtKB:Q6P8X9}.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC       {ECO:0000269|PubMed:15998802}.
CC   -!- SIMILARITY: Belongs to the Flattop family. {ECO:0000305}.
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DR   EMBL; DS496125; EDP03452.1; -; Genomic_DNA.
DR   RefSeq; XP_001692883.1; XM_001692831.1.
DR   PDB; 6U42; EM; 3.40 A; 5H/5I/5J/5K=1-137.
DR   PDB; 6VE7; EM; 3.60 A; H=1-137.
DR   PDBsum; 6U42; -.
DR   PDBsum; 6VE7; -.
DR   AlphaFoldDB; A8IVJ1; -.
DR   SMR; A8IVJ1; -.
DR   STRING; 3055.EDP03452; -.
DR   PaxDb; A8IVJ1; -.
DR   EnsemblPlants; PNW75667; PNW75667; CHLRE_12g536100v5.
DR   GeneID; 5718488; -.
DR   Gramene; PNW75667; PNW75667; CHLRE_12g536100v5.
DR   HOGENOM; CLU_2124208_0_0_1; -.
DR   InParanoid; A8IVJ1; -.
DR   OMA; PRWPKEN; -.
DR   OrthoDB; 1527409at2759; -.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR   InterPro; IPR038797; Fltp.
DR   PANTHER; PTHR34639; PTHR34639; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell projection; Cilium; Flagellum.
FT   CHAIN           1..137
FT                   /note="Protein Flattop homolog"
FT                   /id="PRO_0000432114"
SQ   SEQUENCE   137 AA;  15415 MW;  69664F748C334412 CRC64;
     MSRSYPGEQV EHAFNSKRLK NWEVPAVDKS QAISTSTGTR FGTLQPRSGR TQFIVDDNGH
     LKSGVPKLEK SAFNFTQTTP VFMDSAPRWP KENPTWPKNM KATMGYKGIQ SNYLPTNTVT
     LKAVEVPGTT ERNFNFM