FLXL1_ARATH
ID FLXL1_ARATH Reviewed; 331 AA.
AC Q93V84; Q9LUC0;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Protein FLX-like 1;
DE Short=AtFLXL1;
GN Name=FLXL1; Synonyms=FLL1; OrderedLocusNames=At3g14750; ORFNames=MIE1.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, INTERACTION WITH FRI, AND DISRUPTION PHENOTYPE.
RX PubMed=21282526; DOI=10.1105/tpc.110.075911;
RA Choi K., Kim J., Hwang H.J., Kim S., Park C., Kim S.Y., Lee I.;
RT "The FRIGIDA complex activates transcription of FLC, a strong flowering
RT repressor in Arabidopsis, by recruiting chromatin modification factors.";
RL Plant Cell 23:289-303(2011).
RN [5]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=23864009; DOI=10.1038/ncomms3186;
RA Lee J., Amasino R.M.;
RT "Two FLX family members are non-redundantly required to establish the
RT vernalization requirement in Arabidopsis.";
RL Nat. Commun. 4:2186-2186(2013).
CC -!- FUNCTION: Has no transcriptional activation activity.
CC {ECO:0000269|PubMed:21282526, ECO:0000269|PubMed:23864009}.
CC -!- SUBUNIT: Interacts with FRI. {ECO:0000269|PubMed:21282526}.
CC -!- DISRUPTION PHENOTYPE: No suppression of FRI activity.
CC {ECO:0000269|PubMed:21282526, ECO:0000269|PubMed:23864009}.
CC -!- SIMILARITY: Belongs to the FLX family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02406.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB023038; BAB02406.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE75563.1; -; Genomic_DNA.
DR EMBL; AY035083; AAK59588.1; -; mRNA.
DR EMBL; AY051034; AAK93711.1; -; mRNA.
DR RefSeq; NP_566492.1; NM_112336.5.
DR AlphaFoldDB; Q93V84; -.
DR SMR; Q93V84; -.
DR IntAct; Q93V84; 1.
DR STRING; 3702.AT3G14750.1; -.
DR PaxDb; Q93V84; -.
DR PRIDE; Q93V84; -.
DR ProteomicsDB; 230106; -.
DR EnsemblPlants; AT3G14750.1; AT3G14750.1; AT3G14750.
DR GeneID; 820703; -.
DR Gramene; AT3G14750.1; AT3G14750.1; AT3G14750.
DR KEGG; ath:AT3G14750; -.
DR Araport; AT3G14750; -.
DR TAIR; locus:2089616; AT3G14750.
DR eggNOG; ENOG502QRPR; Eukaryota.
DR HOGENOM; CLU_051930_4_1_1; -.
DR InParanoid; Q93V84; -.
DR OMA; DMQMREL; -.
DR OrthoDB; 1098585at2759; -.
DR PhylomeDB; Q93V84; -.
DR PRO; PR:Q93V84; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q93V84; baseline and differential.
DR Genevisible; Q93V84; AT.
DR GO; GO:0016604; C:nuclear body; IDA:TAIR.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR InterPro; IPR040353; FLX/FLX-like.
DR PANTHER; PTHR33405; PTHR33405; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Developmental protein; Differentiation; Flowering;
KW Reference proteome.
FT CHAIN 1..331
FT /note="Protein FLX-like 1"
FT /id="PRO_0000423735"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 69..252
FT /evidence="ECO:0000255"
FT COMPBIAS 34..48
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 331 AA; 36745 MW; E558B9A7222E0B6F CRC64;
MSGRNRGPPP PSMKGGSYSG LQAPVHQPPF VRGLGGGPVP PPPHPSMIDD SREPQFRVDA
RGLPPQFSIL EDRLAAQNQD VQGLLADNQR LAATHVALKQ ELEVAQHELQ RIMHYIDSLR
AEEEIMMREM YDKSMRSEME LREVDAMRAE IQKIRADIKE FTSGRQELTS QVHLMTQDLA
RLTADLQQIP TLTAEIENTK QELQRARAAI DYEKKGYAEN YEHGKIMEHK LVAMARELEK
LRAEIANSET SAYANGPVGN PGGVAYGGGY GNPEAGYPVN PYQPNYTMNP AQTGVVGYYP
PPYGPQAAWA GGYDPQQQQQ QQPPPQGQGH R
