FLXL3_ARATH
ID FLXL3_ARATH Reviewed; 283 AA.
AC Q9C717; Q9C887;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Protein FLX-like 3;
DE Short=AtFLXL3;
GN Name=FLXL3; Synonyms=FLL3; OrderedLocusNames=At1g55170;
GN ORFNames=F7A10.21, T7N22.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, INTERACTION WITH FRI, AND DISRUPTION PHENOTYPE.
RX PubMed=21282526; DOI=10.1105/tpc.110.075911;
RA Choi K., Kim J., Hwang H.J., Kim S., Park C., Kim S.Y., Lee I.;
RT "The FRIGIDA complex activates transcription of FLC, a strong flowering
RT repressor in Arabidopsis, by recruiting chromatin modification factors.";
RL Plant Cell 23:289-303(2011).
RN [6]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=23864009; DOI=10.1038/ncomms3186;
RA Lee J., Amasino R.M.;
RT "Two FLX family members are non-redundantly required to establish the
RT vernalization requirement in Arabidopsis.";
RL Nat. Commun. 4:2186-2186(2013).
CC -!- FUNCTION: Has no transcriptional activation activity.
CC {ECO:0000269|PubMed:21282526, ECO:0000269|PubMed:23864009}.
CC -!- SUBUNIT: Interacts with FRI. {ECO:0000269|PubMed:21282526}.
CC -!- DISRUPTION PHENOTYPE: No suppression of FRI activity.
CC {ECO:0000269|PubMed:21282526, ECO:0000269|PubMed:23864009}.
CC -!- SIMILARITY: Belongs to the FLX family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51576.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC027034; AAG51576.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC073944; AAG50834.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33197.1; -; Genomic_DNA.
DR EMBL; BT006117; AAP04102.1; -; mRNA.
DR EMBL; AK118721; BAC43315.1; -; mRNA.
DR EMBL; AY084916; AAM61478.1; -; mRNA.
DR PIR; D96593; D96593.
DR RefSeq; NP_564678.1; NM_104390.2.
DR AlphaFoldDB; Q9C717; -.
DR SMR; Q9C717; -.
DR IntAct; Q9C717; 1.
DR STRING; 3702.AT1G55170.1; -.
DR PaxDb; Q9C717; -.
DR PRIDE; Q9C717; -.
DR ProteomicsDB; 230782; -.
DR EnsemblPlants; AT1G55170.1; AT1G55170.1; AT1G55170.
DR GeneID; 841960; -.
DR Gramene; AT1G55170.1; AT1G55170.1; AT1G55170.
DR KEGG; ath:AT1G55170; -.
DR Araport; AT1G55170; -.
DR TAIR; locus:2035751; AT1G55170.
DR eggNOG; ENOG502QTTR; Eukaryota.
DR HOGENOM; CLU_051930_1_1_1; -.
DR InParanoid; Q9C717; -.
DR OMA; EKPRMTR; -.
DR OrthoDB; 1185156at2759; -.
DR PhylomeDB; Q9C717; -.
DR PRO; PR:Q9C717; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C717; baseline and differential.
DR Genevisible; Q9C717; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR InterPro; IPR040353; FLX/FLX-like.
DR PANTHER; PTHR33405; PTHR33405; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Developmental protein; Differentiation; Flowering;
KW Reference proteome.
FT CHAIN 1..283
FT /note="Protein FLX-like 3"
FT /id="PRO_0000423732"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 252..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 40..229
FT /evidence="ECO:0000255"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 283 AA; 33101 MW; F6872D9A18645516 CRC64;
MSGRNRIHRD IRDSYHDHRD LPPERPFLRG PPLLQPPPPS LLEDLQIQEG EIRRQDAEIR
RLLSDNHGLA DDRMVLEREL VAAKEELHRM NLMISDLRAE QDLQLREFSE KRHKLEGDVR
AMESYKKEAS QLRGEVQKLD EIKRELSGNV QLLRKDLAKL QSDNKQIPGM RAEVKDLQKE
LMHARDAIEY EKKEKFELME QRQTMEKNMV SMAREVEKLR AELATVDSRP WGFGGSYGMN
YNNMDGTFRG SYGENDTYLG SSERSQYYSH GSGSQKKPRL DRH
