FLXL4_ARATH
ID FLXL4_ARATH Reviewed; 238 AA.
AC Q9FH51;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Protein FLX-like 4;
DE Short=AtFLXL4;
GN Name=FLXL4; Synonyms=FLL4; OrderedLocusNames=At5g61920; ORFNames=K22G18.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP FUNCTION, AND INTERACTION WITH FRI.
RX PubMed=21282526; DOI=10.1105/tpc.110.075911;
RA Choi K., Kim J., Hwang H.J., Kim S., Park C., Kim S.Y., Lee I.;
RT "The FRIGIDA complex activates transcription of FLC, a strong flowering
RT repressor in Arabidopsis, by recruiting chromatin modification factors.";
RL Plant Cell 23:289-303(2011).
RN [5]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=23864009; DOI=10.1038/ncomms3186;
RA Lee J., Amasino R.M.;
RT "Two FLX family members are non-redundantly required to establish the
RT vernalization requirement in Arabidopsis.";
RL Nat. Commun. 4:2186-2186(2013).
CC -!- FUNCTION: Involved in FLC activation and flowering time control, but
CC has no transcriptional activation activity. Probably part of the FRI-C
CC complex, but is not redundant with FLX. {ECO:0000269|PubMed:21282526,
CC ECO:0000269|PubMed:23864009}.
CC -!- SUBUNIT: Interacts with FRI. {ECO:0000269|PubMed:21282526}.
CC -!- DISRUPTION PHENOTYPE: Early flowering. {ECO:0000269|PubMed:23864009}.
CC -!- SIMILARITY: Belongs to the FLX family. {ECO:0000305}.
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DR EMBL; AB022212; BAB08878.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97536.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97537.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70292.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70294.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70295.1; -; Genomic_DNA.
DR EMBL; DQ447104; ABE66272.1; -; mRNA.
DR RefSeq; NP_001119474.1; NM_001126002.2.
DR RefSeq; NP_001331914.1; NM_001345506.1.
DR RefSeq; NP_001331916.1; NM_001345505.1.
DR RefSeq; NP_001331917.1; NM_001345503.1.
DR RefSeq; NP_200998.1; NM_125585.2.
DR AlphaFoldDB; Q9FH51; -.
DR SMR; Q9FH51; -.
DR BioGRID; 21557; 2.
DR STRING; 3702.AT5G61920.1; -.
DR PaxDb; Q9FH51; -.
DR PRIDE; Q9FH51; -.
DR ProteomicsDB; 230783; -.
DR EnsemblPlants; AT5G61920.1; AT5G61920.1; AT5G61920.
DR EnsemblPlants; AT5G61920.2; AT5G61920.2; AT5G61920.
DR EnsemblPlants; AT5G61920.3; AT5G61920.3; AT5G61920.
DR EnsemblPlants; AT5G61920.5; AT5G61920.5; AT5G61920.
DR EnsemblPlants; AT5G61920.6; AT5G61920.6; AT5G61920.
DR GeneID; 836313; -.
DR Gramene; AT5G61920.1; AT5G61920.1; AT5G61920.
DR Gramene; AT5G61920.2; AT5G61920.2; AT5G61920.
DR Gramene; AT5G61920.3; AT5G61920.3; AT5G61920.
DR Gramene; AT5G61920.5; AT5G61920.5; AT5G61920.
DR Gramene; AT5G61920.6; AT5G61920.6; AT5G61920.
DR KEGG; ath:AT5G61920; -.
DR Araport; AT5G61920; -.
DR TAIR; locus:2156146; AT5G61920.
DR eggNOG; ENOG502QW8B; Eukaryota.
DR HOGENOM; CLU_1216251_0_0_1; -.
DR InParanoid; Q9FH51; -.
DR OMA; HISHIPV; -.
DR OrthoDB; 1292521at2759; -.
DR PhylomeDB; Q9FH51; -.
DR PRO; PR:Q9FH51; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FH51; baseline and differential.
DR Genevisible; Q9FH51; AT.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR InterPro; IPR040353; FLX/FLX-like.
DR PANTHER; PTHR33405; PTHR33405; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Developmental protein; Differentiation; Flowering;
KW Reference proteome.
FT CHAIN 1..238
FT /note="Protein FLX-like 4"
FT /id="PRO_0000423733"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 50..237
FT /evidence="ECO:0000255"
FT COMPBIAS 12..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 238 AA; 27086 MW; A7903F42EC5CEF0F CRC64;
MSSRERIGSN HHSRVSQGMS TSGSSSSRHH DTISSTSDPR HLRDHQISLS DILENKIAVQ
AAEIDRLSND NRKLASSYVA LKEDLTVADR EVQGLRAHIR KTETDHEIQI RSTLEKIAKM
EGMVKNRENI RREVQSAHIE AHRLAREREE LASKVKLGMK DLKKVCLEAE SLEASSQELE
RLKEEHQRLR KEFEEEKSGN VEKLAQLKGM ERKIIGAVKA IEKLRSEIST ARNKAVEN
