FL_ORYSJ
ID FL_ORYSJ Reviewed; 389 AA.
AC Q0JAI1; A3AX14; O24175; Q7XNU1; Q9S9R2;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-MAY-2016, sequence version 2.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Probable transcription factor FL {ECO:0000303|PubMed:9482818};
DE Short=RFL {ECO:0000303|PubMed:9482818};
DE AltName: Full=Protein ABERRANT PANICLE ORGANIZATION 2 {ECO:0000303|PubMed:21910771};
GN Name=FL {ECO:0000303|PubMed:9482818};
GN Synonyms=APO2 {ECO:0000303|PubMed:21910771}, OSL;
GN OrderedLocusNames=Os04g0598300 {ECO:0000305}, LOC_Os04g51000 {ECO:0000305};
GN ORFNames=OsJ_16017 {ECO:0000312|EMBL:EAZ31853.1}, OSJNba0093F12.17;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Toride; TISSUE=Panicle;
RX PubMed=9482818; DOI=10.1073/pnas.95.5.1979;
RA Kyozuka J., Konishi S., Nemoto K., Izawa T., Shimamoto K.;
RT "Down-regulation of RFL, the FLO/LFY homolog of rice, accompanied with
RT panicle branch initiation.";
RL Proc. Natl. Acad. Sci. U.S.A. 95:1979-1982(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION, AND SEQUENCE REVISION TO ARG-321.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, DEVELOPMENTAL STAGE, AND INTERACTION WITH
RP APO1.
RX PubMed=21910771; DOI=10.1111/j.1365-313x.2011.04781.x;
RA Ikeda-Kawakatsu K., Maekawa M., Izawa T., Itoh J.-I., Nagato Y.;
RT "ABERRANT PANICLE ORGANIZATION 2/RFL, the rice ortholog of Arabidopsis
RT LEAFY, suppresses the transition from inflorescence meristem to floral
RT meristem through interaction with APO1.";
RL Plant J. 69:168-180(2012).
CC -!- FUNCTION: Probable transcription factor (By similarity). Together with
CC APO1, involved in the temporal regulation of meristem size and identity
CC during both vegetative and reproductive developments through
CC interaction with APO1 (PubMed:21910771). Promotes flowering
CC (PubMed:21910771). {ECO:0000250|UniProtKB:Q00958,
CC ECO:0000269|PubMed:21910771}.
CC -!- SUBUNIT: Interacts with APO1. {ECO:0000269|PubMed:21910771}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
CC -!- TISSUE SPECIFICITY: In very young panicle but not in mature florets,
CC mature leaves, roots or apical meristems. {ECO:0000269|PubMed:9482818}.
CC -!- DEVELOPMENTAL STAGE: In the vegetative phase, expressed in shoot
CC meristems and leaf primordia. In the reproductive phase, present in the
CC meristems of primary and secondary branches at primordial and
CC elongating stages, but later transiently down-regulated from the
CC meristems, when the meristem identity change from inflorescence to
CC spikelet. Subsequent expression recovery when spikelets are
CC differentiated, with an accumulation in floral meristems and in
CC primordia of all floral organs, including lodicules, stamens, carpels
CC and ovules. {ECO:0000269|PubMed:21910771}.
CC -!- DISRUPTION PHENOTYPE: Several abnormal phenotypes in the vegetative and
CC reproductive phases including short plastochron, late flowering, small
CC panicles, reduced meristems size, aberrant floral organ identities and
CC loss of floral meristem determinacy (PubMed:21910771). Reduced panicles
CC size is associated with reduced number of primary branches due to the
CC precocious formation of spikelet meristems (PubMed:21910771).
CC {ECO:0000269|PubMed:21910771}.
CC -!- SIMILARITY: Belongs to the FLO/LFY family. {ECO:0000305}.
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DR EMBL; AB005620; BAA21547.1; -; mRNA.
DR EMBL; AL607004; CAE03943.3; -; Genomic_DNA.
DR EMBL; AP008210; BAF15656.1; -; Genomic_DNA.
DR EMBL; AP014960; BAS90812.1; -; Genomic_DNA.
DR EMBL; CM000141; EAZ31853.1; -; Genomic_DNA.
DR PIR; T03411; T03411.
DR RefSeq; XP_015635355.1; XM_015779869.1.
DR AlphaFoldDB; Q0JAI1; -.
DR SMR; Q0JAI1; -.
DR STRING; 4530.OS04T0598300-00; -.
DR PaxDb; Q0JAI1; -.
DR PRIDE; Q0JAI1; -.
DR EnsemblPlants; Os04t0598300-01; Os04t0598300-01; Os04g0598300.
DR GeneID; 4336857; -.
DR Gramene; Os04t0598300-01; Os04t0598300-01; Os04g0598300.
DR KEGG; osa:4336857; -.
DR eggNOG; ENOG502QSDD; Eukaryota.
DR InParanoid; Q0JAI1; -.
DR OMA; IFNTHPR; -.
DR OrthoDB; 1031599at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000007752; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; Q0JAI1; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0010074; P:maintenance of meristem identity; IMP:UniProtKB.
DR GO; GO:1905613; P:regulation of developmental vegetative growth; IMP:UniProtKB.
DR GO; GO:0009909; P:regulation of flower development; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.10.4180.10; -; 1.
DR InterPro; IPR035209; FLO/LFY_C.
DR InterPro; IPR002910; FLO_LFY.
DR InterPro; IPR038276; Floricaula/leafy_C_sf.
DR InterPro; IPR035079; LFY_SAM.
DR PANTHER; PTHR36079; PTHR36079; 1.
DR Pfam; PF17538; C_LFY_FLO; 1.
DR Pfam; PF01698; SAM_LFY; 1.
PE 1: Evidence at protein level;
KW Activator; Developmental protein; Differentiation; DNA-binding; Flowering;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..389
FT /note="Probable transcription factor FL"
FT /id="PRO_0000129150"
FT DNA_BIND 221..225
FT /evidence="ECO:0000250|UniProtKB:Q00958"
FT DNA_BIND 290..297
FT /evidence="ECO:0000250|UniProtKB:Q00958"
FT DNA_BIND 361..364
FT /evidence="ECO:0000250|UniProtKB:Q00958"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 161..168
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT COMPBIAS 17..41
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..180
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 268
FT /note="Interaction with DNA"
FT /evidence="ECO:0000250|UniProtKB:Q00958"
FT SITE 275
FT /note="Interaction with DNA"
FT /evidence="ECO:0000250|UniProtKB:Q00958"
FT SITE 279
FT /note="Interaction with DNA"
FT /evidence="ECO:0000250|UniProtKB:Q00958"
FT SITE 326
FT /note="Interaction with DNA"
FT /evidence="ECO:0000250|UniProtKB:Q00958"
FT CONFLICT 321
FT /note="R -> P (in Ref. 2; CAE03943 and 3; BAF15656)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 389 AA; 42530 MW; 5132AA6A34B0868A CRC64;
MDPNDAFSAA HPFRWDLGPP APAPVPPPPP PPPPPPPANV PRELEELVAG YGVRMSTVAR
ISELGFTAST LLAMTERELD DMMAALAGLF RWDLLLGERF GLRAALRAER GRLMSLGGRH
HGHQSGSTVD GASQEVLSDE HDMAGSGGMG DDDNGRRMVT GKKQAKKGSA ARKGKKARRK
KVDDLRLDMQ EDEMDCCDED GGGGSESTES SAGGGGGERQ REHPFVVTEP GEVARAKKNG
LDYLFHLYEQ CRLFLLQVQS MAKLHGHKSP TKVTNQVFRY AKKVGASYIN KPKMRHYVHC
YALHCLDEEA SDALRRAYKA RGENVGAWRQ ACYAPLVDIS ARHGFDIDAV FAAHPRLAIW
YVPTRLRQLC HQARSSHAAA AAALPPPLF
