ID   FMAJ_DICNO              Reviewed;         160 AA.
AC   P19528;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Type IV major fimbrial protein FimA;
DE   AltName: Full=351 antigen;
DE   AltName: Full=Pilin;
DE   AltName: Full=Serogroup H;
DE   Flags: Precursor;
GN   Name=fimA;
OS   Dichelobacter nodosus (Bacteroides nodosus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Cardiobacteriales;
OC   Cardiobacteriaceae; Dichelobacter.
OX   NCBI_TaxID=870;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serogroup H isolate 351;
RX   PubMed=2621448; DOI=10.1099/00221287-135-5-1113;
RA   Hoyne P.A., Elleman T.C., McKern N.M., Stewart D.J.;
RT   "Sequence of pilin from Bacteroides nodosus 351 (Serogroup H) and
RT   implications for serogroup classification.";
RL   J. Gen. Microbiol. 135:1113-1122(1989).
CC   -!- FUNCTION: Major component of the type IV fimbriae that plays an
CC       essential role in twitching motility, natural transformation, and
CC       protease secretion. {ECO:0000250|UniProtKB:A5EWR9}.
CC   -!- SUBUNIT: The pili are polar flexible filaments of about 5.4 nanometers
CC       diameter and 2.5 micrometers average length; they consist of only a
CC       single polypeptide chain arranged in a helical configuration of five
CC       subunits per turn in the assembled pilus.
CC   -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000250|UniProtKB:A5EWR9}. Membrane
CC       {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the N-Me-Phe pilin family. {ECO:0000305}.
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DR   EMBL; M26980; AAA23336.1; -; Genomic_DNA.
DR   PIR; A37167; A37167.
DR   AlphaFoldDB; P19528; -.
DR   SMR; P19528; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR   InterPro; IPR000983; Bac_GSPG_pilin.
DR   InterPro; IPR012902; N_methyl_site.
DR   InterPro; IPR001082; Pilin.
DR   InterPro; IPR045584; Pilin-like.
DR   Pfam; PF07963; N_methyl; 1.
DR   Pfam; PF00114; Pilin; 1.
DR   PRINTS; PR00813; BCTERIALGSPG.
DR   SUPFAM; SSF54523; SSF54523; 1.
DR   TIGRFAMs; TIGR02532; IV_pilin_GFxxxE; 1.
DR   PROSITE; PS00409; PROKAR_NTER_METHYL; 1.
PE   3: Inferred from homology;
KW   Fimbrium; Membrane; Methylation; Transmembrane; Transmembrane helix.
FT   PROPEP          1..7
FT                   /note="Leader sequence"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01070"
FT                   /id="PRO_0000024140"
FT   CHAIN           8..160
FT                   /note="Type IV major fimbrial protein FimA"
FT                   /id="PRO_0000024141"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         8
FT                   /note="N-methylphenylalanine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01070"
SQ   SEQUENCE   160 AA;  17170 MW;  3160DAEAFE87ABAA CRC64;
     MKSLQKGFTL IELMIVVAII GILAAIAIPQ YQNYIARSQV SRVMSETGQM RTAIETCLLD
     GKKADECFIG WTKSNLLGAS GSPSSSNDST ADHPGQGGLV IDYKLEADAT NAITATFGQN
     AAATLHGKAL KWTRDPKATW SCSTDVELKF RPTGCKDDLK