ID   FMC1_MOUSE              Reviewed;         113 AA.
AC   Q9CR13;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Protein FMC1 homolog;
DE   AltName: Full=Formation of mitochondrial complex V assembly factor 1 {ECO:0000312|MGI:MGI:1913367};
GN   Name=Fmc1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Embryo, Small intestine, and Tongue;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Heart, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- FUNCTION: Plays a role in the assembly/stability of the mitochondrial
CC       membrane ATP synthase (F(1)F(0) ATP synthase or Complex V).
CC       {ECO:0000250|UniProtKB:Q96HJ9}.
CC   -!- SUBUNIT: Interacts with ATPAF2. {ECO:0000250|UniProtKB:Q96HJ9}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q96HJ9}.
CC   -!- SIMILARITY: Belongs to the FMC1 family. {ECO:0000305}.
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DR   EMBL; AK003231; BAC25025.1; -; mRNA.
DR   EMBL; AK008291; BAB25581.1; -; mRNA.
DR   EMBL; AK009186; BAB26127.1; -; mRNA.
DR   EMBL; BC059710; AAH59710.1; -; mRNA.
DR   CCDS; CCDS20014.1; -.
DR   RefSeq; NP_079639.1; NM_025363.3.
DR   AlphaFoldDB; Q9CR13; -.
DR   BioGRID; 211226; 2.
DR   STRING; 10090.ENSMUSP00000019833; -.
DR   PhosphoSitePlus; Q9CR13; -.
DR   EPD; Q9CR13; -.
DR   MaxQB; Q9CR13; -.
DR   PaxDb; Q9CR13; -.
DR   PeptideAtlas; Q9CR13; -.
DR   PRIDE; Q9CR13; -.
DR   ProteomicsDB; 267485; -.
DR   Antibodypedia; 71139; 8 antibodies from 4 providers.
DR   DNASU; 66117; -.
DR   Ensembl; ENSMUST00000019833; ENSMUSP00000019833; ENSMUSG00000019689.
DR   GeneID; 66117; -.
DR   KEGG; mmu:66117; -.
DR   UCSC; uc009bki.1; mouse.
DR   CTD; 154791; -.
DR   MGI; MGI:1913367; Fmc1.
DR   VEuPathDB; HostDB:ENSMUSG00000019689; -.
DR   eggNOG; ENOG502S1MM; Eukaryota.
DR   GeneTree; ENSGT00390000012258; -.
DR   HOGENOM; CLU_159000_0_0_1; -.
DR   InParanoid; Q9CR13; -.
DR   OMA; QEAHHAS; -.
DR   OrthoDB; 1630277at2759; -.
DR   PhylomeDB; Q9CR13; -.
DR   TreeFam; TF321497; -.
DR   BioGRID-ORCS; 66117; 1 hit in 72 CRISPR screens.
DR   ChiTaRS; Fmc1; mouse.
DR   PRO; PR:Q9CR13; -.
DR   Proteomes; UP000000589; Chromosome 6.
DR   RNAct; Q9CR13; protein.
DR   Bgee; ENSMUSG00000019689; Expressed in ileal epithelium and 251 other tissues.
DR   Genevisible; Q9CR13; MM.
DR   GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR   GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; ISS:UniProtKB.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IDA:MGI.
DR   GO; GO:0061469; P:regulation of type B pancreatic cell proliferation; IDA:MGI.
DR   InterPro; IPR037667; FMC1_homologue.
DR   PANTHER; PTHR31716; PTHR31716; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..113
FT                   /note="Protein FMC1 homolog"
FT                   /id="PRO_0000328781"
FT   REGION          90..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   113 AA;  12695 MW;  33EDF505E255F0C8 CRC64;
     MAALGSPART LRGLLRELRY LNAATGRPYR DTAAYRYLVK AFRAHRVTSE KLCRAQHELH
     FQAATYLCLL SSIRQHVALH QEFHGKGERS VEESAGLVGL QLPRQPGGKG WEP