FMC1_RAT
ID FMC1_RAT Reviewed; 113 AA.
AC Q4G012;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Protein FMC1 homolog;
DE AltName: Full=Formation of mitochondrial complex V assembly factor 1 homolog {ECO:0000312|RGD:1559476};
GN Name=Fmc1 {ECO:0000312|RGD:1559476};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Spleen;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Plays a role in the assembly/stability of the mitochondrial
CC membrane ATP synthase (F(1)F(0) ATP synthase or Complex V).
CC {ECO:0000250|UniProtKB:Q96HJ9}.
CC -!- SUBUNIT: Interacts with ATPAF2. {ECO:0000250|UniProtKB:Q96HJ9}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q96HJ9}.
CC -!- SIMILARITY: Belongs to the FMC1 family. {ECO:0000305}.
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DR EMBL; BC098843; AAH98843.1; -; mRNA.
DR RefSeq; NP_001032884.1; NM_001037795.1.
DR AlphaFoldDB; Q4G012; -.
DR SMR; Q4G012; -.
DR STRING; 10116.ENSRNOP00000007544; -.
DR iPTMnet; Q4G012; -.
DR PhosphoSitePlus; Q4G012; -.
DR PaxDb; Q4G012; -.
DR Ensembl; ENSRNOT00000007544; ENSRNOP00000007544; ENSRNOG00000005618.
DR GeneID; 500087; -.
DR KEGG; rno:500087; -.
DR UCSC; RGD:1559476; rat.
DR CTD; 154791; -.
DR RGD; 1559476; Fmc1.
DR eggNOG; ENOG502S1MM; Eukaryota.
DR GeneTree; ENSGT00390000012258; -.
DR HOGENOM; CLU_159000_0_0_1; -.
DR InParanoid; Q4G012; -.
DR OMA; QEAHHAS; -.
DR OrthoDB; 1630277at2759; -.
DR PhylomeDB; Q4G012; -.
DR TreeFam; TF321497; -.
DR PRO; PR:Q4G012; -.
DR Proteomes; UP000002494; Chromosome 4.
DR Bgee; ENSRNOG00000005618; Expressed in heart and 20 other tissues.
DR Genevisible; Q4G012; RN.
DR GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; ISS:UniProtKB.
DR GO; GO:0050995; P:negative regulation of lipid catabolic process; ISO:RGD.
DR GO; GO:0061469; P:regulation of type B pancreatic cell proliferation; ISO:RGD.
DR InterPro; IPR037667; FMC1_homologue.
DR PANTHER; PTHR31716; PTHR31716; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome.
FT CHAIN 1..113
FT /note="Protein FMC1 homolog"
FT /id="PRO_0000328782"
FT REGION 94..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 113 AA; 12745 MW; 33F10654A740F0C8 CRC64;
MAALGSPART LRGLLRELRY LNAATGRPYR DTAAYRYLVK AFRAHRVTSE KLCRAQHELH
FQAATYLCLL RSIRQHVALH QEFHGKGERS VEESAGLVGL QLPHQPGGKG WEP