ID   FMF2_ECOL6              Reviewed;         188 AA.
AC   P62608; P02972;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=F7-2 fimbrial protein;
DE   AltName: Full=F7-2 pilin;
DE   Flags: Precursor;
GN   Name=F7-2; Synonyms=papA; OrderedLocusNames=c3592;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC       the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC       numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC       of specific host organs. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Fimbrium.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN82040.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE014075; AAN82040.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000597756.1; NC_004431.1.
DR   AlphaFoldDB; P62608; -.
DR   SMR; P62608; -.
DR   STRING; 199310.c3592; -.
DR   EnsemblBacteria; AAN82040; AAN82040; c3592.
DR   KEGG; ecc:c3592; -.
DR   eggNOG; COG3539; Bacteria.
DR   HOGENOM; CLU_088965_3_1_6; -.
DR   OMA; PFYIHLE; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Fimbrium; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250"
FT   CHAIN           22..188
FT                   /note="F7-2 fimbrial protein"
FT                   /id="PRO_0000009188"
FT   DISULFID        43..82
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   188 AA;  19184 MW;  0EEF750CFD843157 CRC64;
     MIKSVIAGAV AMAVVSFGAY AAPTIPQGQG KVTFNGTVVD APCGIDAQSA DQSIDFGQVS
     KLFLENDGES QPKSFDIKLI NCDITNFKKA AGGGGAKTGT VSLTFSGVPS GPQSDMLQTV
     GATNTAIVVT DPHGKRVKFD GATATGVSYL VDGDNTIHFT AAVRKDGSGN PVTEGAFSAV
     ANFNLTYQ