ID   FMF2_ECOLX              Reviewed;         188 AA.
AC   P62607; P02972;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=F7-2 fimbrial protein;
DE   AltName: Full=F7-2 pilin;
DE   Flags: Precursor;
GN   Name=F7-2; Synonyms=papA;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AD110 / UPEC;
RX   PubMed=6152241; DOI=10.1016/0378-1119(84)90035-0;
RA   van Die I., Bergmans H.;
RT   "Nucleotide sequence of the gene encoding the F72 fimbrial subunit of a
RT   uropathogenic Escherichia coli strain.";
RL   Gene 32:83-90(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1682251; DOI=10.1128/iai.59.11.3849-3858.1991;
RA   Denich K., Blyn L.B., Craiu A., Braaten B.A., Hardy J., Low D.A.,
RA   O'Hanley P.D.;
RT   "DNA sequences of three papA genes from uropathogenic Escherichia coli
RT   strains: evidence of structural and serological conservation.";
RL   Infect. Immun. 59:3849-3858(1991).
CC   -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC       the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC       numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC       of specific host organs.
CC   -!- SUBCELLULAR LOCATION: Fimbrium.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR   EMBL; M12861; AAA23778.1; -; Genomic_DNA.
DR   EMBL; M68060; AAA24278.1; -; Genomic_DNA.
DR   PIR; A03496; YQECF2.
DR   RefSeq; WP_000597756.1; NZ_WNTO01000033.1.
DR   AlphaFoldDB; P62607; -.
DR   SMR; P62607; -.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Fimbrium; Signal.
FT   SIGNAL          1..21
FT   CHAIN           22..188
FT                   /note="F7-2 fimbrial protein"
FT                   /id="PRO_0000009187"
FT   DISULFID        43..82
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   188 AA;  19184 MW;  0EEF750CFD843157 CRC64;
     MIKSVIAGAV AMAVVSFGAY AAPTIPQGQG KVTFNGTVVD APCGIDAQSA DQSIDFGQVS
     KLFLENDGES QPKSFDIKLI NCDITNFKKA AGGGGAKTGT VSLTFSGVPS GPQSDMLQTV
     GATNTAIVVT DPHGKRVKFD GATATGVSYL VDGDNTIHFT AAVRKDGSGN PVTEGAFSAV
     ANFNLTYQ