ID   FMF4_ECOLX              Reviewed;         277 AA.
AC   P11900;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=F41 fimbrial protein;
DE   AltName: Full=Adhesin F41;
DE   Flags: Precursor;
GN   Name=FimF41a;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=B41;
RX   PubMed=2566150; DOI=10.1093/nar/17.7.2849;
RA   Fidock D.A., McNicholas P.A., Lehrbach P.R.;
RT   "Nucleotide sequence of the F41 fimbriae subunit gene in Escherichia coli
RT   B41.";
RL   Nucleic Acids Res. 17:2849-2849(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2902070; DOI=10.1128/jb.170.10.4890-4896.1988;
RA   Anderson D.G., Moseley S.L.;
RT   "Escherichia coli F41 adhesin: genetic organization, nucleotide sequence,
RT   and homology with the K88 determinant.";
RL   J. Bacteriol. 170:4890-4896(1988).
CC   -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC       the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC       numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC       of specific host organs.
CC   -!- SUBCELLULAR LOCATION: Fimbrium.
CC   -!- SIMILARITY: Belongs to the fimbrial K88 protein family. {ECO:0000305}.
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DR   EMBL; X14354; CAA32535.1; -; Genomic_DNA.
DR   EMBL; M21788; AAA23421.1; -; Genomic_DNA.
DR   PIR; S04072; S04072.
DR   RefSeq; WP_063080188.1; NZ_VTAJ01000023.1.
DR   AlphaFoldDB; P11900; -.
DR   SMR; P11900; -.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Fimbrium; Signal.
FT   SIGNAL          1..22
FT   CHAIN           23..277
FT                   /note="F41 fimbrial protein"
FT                   /id="PRO_0000009190"
FT   CONFLICT        156
FT                   /note="D -> N (in Ref. 2; AAA23421)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        166..167
FT                   /note="IG -> TS (in Ref. 2; AAA23421)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        211
FT                   /note="Q -> K (in Ref. 2; AAA23421)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        229
FT                   /note="S -> P (in Ref. 2; AAA23421)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        235
FT                   /note="N -> D (in Ref. 2; AAA23421)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   277 AA;  29001 MW;  EFA04A1A26C61AE2 CRC64;
     MKKTLIALAV AASAAVSGSV MAADWTEGQP GDIIIGGEIT SPSVKWLWKT GEGLSSFSNT
     TNEIVKRKLN ISVPTDELFL AAKMSDGIKG VFVGNTLIPK IEMASYDGSV ITPSFTSNTA
     MDIAVKVKNS GDNTELGTLS VPLSFGAAVA TIFDGDTTDS AVAHIIGGSA GTVFEGLVNP
     GRFTDQNIAY KWNGLSKAEM AGYVEKLMPG QSASTSYSGF HNWDDLSHSN YTSANKASYL
     SYGSGVSAGS TLVMNLNKDV AGRLEWVAPV TITVIYS