ID   FMKH_MICOL              Reviewed;         126 AA.
AC   Q08324;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Fortimicin KH epimerase;
DE            Short=FMKH epimerase;
DE            EC=5.-.-.-;
DE   Flags: Fragment;
GN   Name=fms11;
OS   Micromonospora olivasterospora.
OC   Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
OC   Micromonospora.
OX   NCBI_TaxID=1880;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8486289; DOI=10.1016/0378-1119(93)90617-c;
RA   Ohta T., Hasegawa M.;
RT   "Analysis of the self-defense gene (fmrO) of a fortimicin A (astromicin)
RT   producer, Micromonospora olivasterospora: comparison with other
RT   aminoglycoside-resistance-encoding genes.";
RL   Gene 127:63-69(1993).
CC   -!- FUNCTION: Catalyzes the conversion of fortimicin KH to fortimicin KR.
CC   -!- PATHWAY: Antibiotic biosynthesis; fortimicin biosynthesis.
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DR   EMBL; D13171; BAA02449.1; -; Genomic_DNA.
DR   PIR; PN0542; PN0542.
DR   AlphaFoldDB; Q08324; -.
DR   UniPathway; UPA00184; -.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Antibiotic biosynthesis; Isomerase.
FT   CHAIN           1..>126
FT                   /note="Fortimicin KH epimerase"
FT                   /id="PRO_0000087314"
FT   NON_TER         126
SQ   SEQUENCE   126 AA;  14185 MW;  1435C0676F2B83EB CRC64;
     MERPITAART ARSFGLATEI QFCRSHHRER DEEIIAALAA AGEPYVVLEL LDRGRAREML
     QVWRGHRVEE LSECDDLTTT LHATGDVYAC CQLDIGVDQM KRTPVFLGSI RSADSDAAAR
     DRREQL