FMP10_YEAST
ID FMP10_YEAST Reviewed; 244 AA.
AC P40098; D3DM91;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Uncharacterized mitochondrial membrane protein FMP10;
GN Name=FMP10; OrderedLocusNames=YER182W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169868;
RA Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA Botstein D., Davis R.W.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL Nature 387:78-81(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 76625 / YPH499;
RX PubMed=14576278; DOI=10.1073/pnas.2135385100;
RA Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E.,
RA Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P.,
RA Pfanner N., Meisinger C.;
RT "The proteome of Saccharomyces cerevisiae mitochondria.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003).
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- MISCELLANEOUS: Present with 1920 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the FMP10 family. {ECO:0000305}.
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DR EMBL; U18922; AAB64709.1; -; Genomic_DNA.
DR EMBL; BK006939; DAA07845.1; -; Genomic_DNA.
DR PIR; S50685; S50685.
DR RefSeq; NP_011109.3; NM_001179072.3.
DR AlphaFoldDB; P40098; -.
DR SMR; P40098; -.
DR BioGRID; 36936; 35.
DR DIP; DIP-6536N; -.
DR IntAct; P40098; 4.
DR STRING; 4932.YER182W; -.
DR MaxQB; P40098; -.
DR PaxDb; P40098; -.
DR PRIDE; P40098; -.
DR EnsemblFungi; YER182W_mRNA; YER182W; YER182W.
DR GeneID; 856931; -.
DR KEGG; sce:YER182W; -.
DR SGD; S000000984; FMP10.
DR VEuPathDB; FungiDB:YER182W; -.
DR eggNOG; KOG4781; Eukaryota.
DR HOGENOM; CLU_052827_1_1_1; -.
DR InParanoid; P40098; -.
DR OMA; IYHLGMK; -.
DR BioCyc; YEAST:G3O-30339-MON; -.
DR PRO; PR:P40098; -.
DR Proteomes; UP000002311; Chromosome V.
DR RNAct; P40098; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR InterPro; IPR029069; HotDog_dom_sf.
DR SUPFAM; SSF54637; SSF54637; 1.
PE 1: Evidence at protein level;
KW Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..244
FT /note="Uncharacterized mitochondrial membrane protein
FT FMP10"
FT /id="PRO_0000202660"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 244 AA; 27698 MW; A78338C86EA52766 CRC64;
MFKRIAIAQI RTYTNGVVFK TASKPKRRWI PWTIFGGSFL GGWYLTQHMT FTDLLAYWRY
DALPKNADEV VKYHADLNRR LNGLPIVKQL ENAGFVQVIA NEEENLLVSR ALNTPGGVAI
PPRVYYNPSR RETVGLYHLG MKLTGYPFLI HGGILATVIE DLMKEAIRLE KGTKNINQET
KNLSISYKFP TLANQFVVVR TTDLQQYGNK TKLKAELMDQ SGNRTLVKAN ATFSSEQGNP
KEEK
