ID   FMP46_SCHPO             Reviewed;         121 AA.
AC   Q9UTA2;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Putative redox protein fmp46, mitochondrial;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=fmp46; ORFNames=SPAC25B8.18;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Putative mitochondrial redox protein which could be involved
CC       in the reduction of small toxic molecules. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the FMP46 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB61784.1; -; Genomic_DNA.
DR   PIR; T50205; T50205.
DR   RefSeq; NP_594478.1; NM_001019907.2.
DR   AlphaFoldDB; Q9UTA2; -.
DR   SMR; Q9UTA2; -.
DR   BioGRID; 279185; 3.
DR   MaxQB; Q9UTA2; -.
DR   PaxDb; Q9UTA2; -.
DR   EnsemblFungi; SPAC25B8.18.1; SPAC25B8.18.1:pep; SPAC25B8.18.
DR   GeneID; 2542735; -.
DR   KEGG; spo:SPAC25B8.18; -.
DR   PomBase; SPAC25B8.18; -.
DR   VEuPathDB; FungiDB:SPAC25B8.18; -.
DR   HOGENOM; CLU_2039413_0_0_1; -.
DR   InParanoid; Q9UTA2; -.
DR   OMA; RPCLVDW; -.
DR   PhylomeDB; Q9UTA2; -.
DR   PRO; PR:Q9UTA2; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR012882; Fmp46.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR28071; PTHR28071; 1.
DR   Pfam; PF07955; DUF1687; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Oxidoreductase; Reference proteome; Transit peptide.
FT   TRANSIT         1..17
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..121
FT                   /note="Putative redox protein fmp46, mitochondrial"
FT                   /id="PRO_0000374044"
FT   ACT_SITE        96
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   121 AA;  13907 MW;  24421BF0DE2F4B9B CRC64;
     MFGLTTKRIL TLFTKKRQTL VEQKLTEYMI AGEKTDNQML HFKLQVETAT PTLDQLNIML
     SNIGKDKSDL LVAGATSIED ALTKYQHDNQ LFRRPCLVDW DKGKVSPYSI LLQTRDFSKL
     L