ID   3MGH_RICAE              Reviewed;         183 AA.
AC   C3PN66;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=RAF_ORF0446;
OS   Rickettsia africae (strain ESF-5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=347255;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ESF-5;
RX   PubMed=19379498; DOI=10.1186/1471-2164-10-166;
RA   Fournier P.-E., El Karkouri K., Leroy Q., Robert C., Giumelli B.,
RA   Renesto P., Socolovschi C., Parola P., Audic S., Raoult D.;
RT   "Analysis of the Rickettsia africae genome reveals that virulence
RT   acquisition in Rickettsia species may be explained by genome reduction.";
RL   BMC Genomics 10:166-166(2009).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; CP001612; ACP53376.1; -; Genomic_DNA.
DR   RefSeq; WP_012719608.1; NC_012633.1.
DR   AlphaFoldDB; C3PN66; -.
DR   SMR; C3PN66; -.
DR   PRIDE; C3PN66; -.
DR   EnsemblBacteria; ACP53376; ACP53376; RAF_ORF0446.
DR   KEGG; raf:RAF_ORF0446; -.
DR   HOGENOM; CLU_060471_4_1_5; -.
DR   OMA; VEAYHHT; -.
DR   Proteomes; UP000002305; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 2.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..183
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_1000211764"
SQ   SEQUENCE   183 AA;  20476 MW;  B3263DE74C0E8651 CRC64;
     MNKLIPVPRE FFARDTNVVS TELIGKALYF QGKTAIITET ESYIGQNDPA CHAARGRTKR
     TDIMFGPAGF SYVYLIYGMY YCLNFVTEAK GFPAATLIRG VHVISPENLY LNGPGKLCKY
     LGINISHNKC DLINNNEFFV GDIGLKLPYS TTARIGITKG TDKLWRYVVT DITNLISQYN
     VQP