ID   3MGH_RICFE              Reviewed;         177 AA.
AC   Q4UM12;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=RF_0560;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; CP000053; AAY61411.1; -; Genomic_DNA.
DR   RefSeq; WP_011270892.1; NC_007109.1.
DR   AlphaFoldDB; Q4UM12; -.
DR   SMR; Q4UM12; -.
DR   STRING; 315456.RF_0560; -.
DR   EnsemblBacteria; AAY61411; AAY61411; RF_0560.
DR   KEGG; rfe:RF_0560; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_4_1_5; -.
DR   OMA; VEAYHHT; -.
DR   OrthoDB; 1385409at2; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 2.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..177
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265055"
SQ   SEQUENCE   177 AA;  19932 MW;  E2D06F077B35F3C8 CRC64;
     MNKLILLPRE FFARDTNLVS TELIGKVLYF QGKTAIITET ESYIGQDDPA CHAARGRTKR
     TDIMFGPAGF SYVYLIYGMY YCLNFVTETE GFPAATLIRG VHVISPENLY LNGPGKLCKY
     LGINISHNKC DLINNNEFFV SDIGLKLPYS TTTRIGITKG TDKLWRYVVT DIIRLPA