ID   3MGH_RICPR              Reviewed;         217 AA.
AC   Q9ZDH7;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase;
DE            EC=3.2.2.-;
GN   OrderedLocusNames=RP351;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ235271; CAA14811.1; -; Genomic_DNA.
DR   PIR; A71692; A71692.
DR   RefSeq; NP_220734.1; NC_000963.1.
DR   RefSeq; WP_004599421.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZDH7; -.
DR   SMR; Q9ZDH7; -.
DR   STRING; 272947.RP351; -.
DR   PRIDE; Q9ZDH7; -.
DR   EnsemblBacteria; CAA14811; CAA14811; CAA14811.
DR   GeneID; 57569477; -.
DR   KEGG; rpr:RP351; -.
DR   PATRIC; fig|272947.5.peg.361; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_0_2_5; -.
DR   OMA; LPWRWYL; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..217
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000100102"
FT   DOMAIN          105..145
FT                   /note="RPE2 insert"
SQ   SEQUENCE   217 AA;  24809 MW;  0B5A4DBE000A7942 CRC64;
     MNKLIPLPRE FFARDTNLVS TELIGKVLYF QGTTAIITET ESYIGEDDPA CHAARGRTKR
     TDVMFGPAGF SYVYLIYGMY YCLNFVTEDE GFPAATLIRG VYVISHNNVY TIDTAKIKSQ
     ITDEKTQSII IRKNRRIMKF YIPNLKASNL YLNGPGKLCK YLGINTSYNK CDLINNKDFF
     VSDIGLNLPY YSTTRIGITK GTDKLWRYIV TDPKMLY