ID   FND11_MOUSE             Reviewed;         326 AA.
AC   Q80WB0; A2AS01;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Fibronectin type III domain-containing protein 11;
GN   Name=Fndc11;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL845506; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC051628; AAH51628.1; -; mRNA.
DR   CCDS; CCDS17205.1; -.
DR   RefSeq; NP_955016.1; NM_199312.3.
DR   RefSeq; XP_011238251.1; XM_011239949.1.
DR   AlphaFoldDB; Q80WB0; -.
DR   STRING; 10090.ENSMUSP00000056320; -.
DR   iPTMnet; Q80WB0; -.
DR   PhosphoSitePlus; Q80WB0; -.
DR   PaxDb; Q80WB0; -.
DR   PRIDE; Q80WB0; -.
DR   ProteomicsDB; 271777; -.
DR   Antibodypedia; 29791; 112 antibodies from 20 providers.
DR   DNASU; 332713; -.
DR   Ensembl; ENSMUST00000050026; ENSMUSP00000056320; ENSMUSG00000047841.
DR   GeneID; 332713; -.
DR   KEGG; mmu:332713; -.
DR   UCSC; uc008olm.1; mouse.
DR   CTD; 79025; -.
DR   MGI; MGI:3051572; Fndc11.
DR   VEuPathDB; HostDB:ENSMUSG00000047841; -.
DR   eggNOG; ENOG502QW8H; Eukaryota.
DR   GeneTree; ENSGT00390000006008; -.
DR   InParanoid; Q80WB0; -.
DR   OMA; RFQRMKK; -.
DR   PhylomeDB; Q80WB0; -.
DR   TreeFam; TF338188; -.
DR   BioGRID-ORCS; 332713; 4 hits in 74 CRISPR screens.
DR   PRO; PR:Q80WB0; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q80WB0; protein.
DR   Bgee; ENSMUSG00000047841; Expressed in seminiferous tubule of testis and 7 other tissues.
DR   ExpressionAtlas; Q80WB0; baseline and differential.
DR   Genevisible; Q80WB0; MM.
DR   CDD; cd00063; FN3; 1.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR039581; FNDC11.
DR   PANTHER; PTHR14537; PTHR14537; 1.
DR   Pfam; PF17744; DUF5581; 1.
DR   SUPFAM; SSF49265; SSF49265; 1.
DR   PROSITE; PS50853; FN3; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..326
FT                   /note="Fibronectin type III domain-containing protein 11"
FT                   /id="PRO_0000232868"
FT   DOMAIN          212..310
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT   REGION          304..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        310..326
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   326 AA;  37356 MW;  C1FA529E7AF17748 CRC64;
     MNFQVTGLAL DKMKLDSPHS FLDAEEVEEA EDQQLLEPEA WRTYMERRNV LREFLTTDLS
     PQLLKRHHAR MQLLKKCSYY IEILPKHLAL GDQNPLVLPN TMFQLIDPWK FQRMKKVGTA
     QTKIQLLLLG DLLEQLDHGR AALDALLEAP DPRPFLAGWG LVEQQLADLS VVMDNFLAMM
     VPGHLHVKHR LVSDIGATKI PHIRLMLSTK MPVMFDRKES VAHQDWVSLR WFVTIQPAAP
     EQYELRFKLL EPRTQQECTQ CGIVPVAACT FDVHNLLPNR TYKFTIKRAE SYTLVYEPWR
     DSLTLQTTPG PPEGPAPRLG EPPAGL