FND3A_CHICK
ID FND3A_CHICK Reviewed; 1198 AA.
AC Q5ZJP5;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Fibronectin type-III domain-containing protein 3a;
GN Name=FNDC3A; Synonyms=FNDC3; ORFNames=RCJMB04_16k12;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FNDC3 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAG32048.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ720389; CAG32048.1; ALT_INIT; mRNA.
DR RefSeq; NP_001012844.1; NM_001012826.2.
DR AlphaFoldDB; Q5ZJP5; -.
DR SMR; Q5ZJP5; -.
DR STRING; 9031.ENSGALP00000027412; -.
DR PaxDb; Q5ZJP5; -.
DR GeneID; 418863; -.
DR KEGG; gga:418863; -.
DR CTD; 22862; -.
DR VEuPathDB; HostDB:geneid_418863; -.
DR eggNOG; ENOG502QRT8; Eukaryota.
DR InParanoid; Q5ZJP5; -.
DR OrthoDB; 633003at2759; -.
DR PhylomeDB; Q5ZJP5; -.
DR PRO; PR:Q5ZJP5; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 9.
DR Gene3D; 2.60.40.10; -; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR Pfam; PF00041; fn3; 6.
DR SMART; SM00060; FN3; 9.
DR SUPFAM; SSF49265; SSF49265; 6.
DR PROSITE; PS50853; FN3; 9.
PE 2: Evidence at transcript level;
KW Golgi apparatus; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..1198
FT /note="Fibronectin type-III domain-containing protein 3a"
FT /id="PRO_0000379878"
FT TRANSMEM 1172..1192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 269..370
FT /note="Fibronectin type-III 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT DOMAIN 374..466
FT /note="Fibronectin type-III 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT DOMAIN 470..563
FT /note="Fibronectin type-III 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT DOMAIN 567..661
FT /note="Fibronectin type-III 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT DOMAIN 665..758
FT /note="Fibronectin type-III 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT DOMAIN 762..852
FT /note="Fibronectin type-III 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT DOMAIN 864..951
FT /note="Fibronectin type-III 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT DOMAIN 952..1045
FT /note="Fibronectin type-III 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT DOMAIN 1046..1151
FT /note="Fibronectin type-III 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT REGION 189..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1198 AA; 131561 MW; F74FC5307313A3AA CRC64;
MAEHPPLLDT SSIISSEIPL LTSPIVSGDG AQQVILVQVN PGEAFTIRRE DGQFQCITGP
AQVPMMSPNG SVPTIYVPPG YAPQVIEDNG VRRVVVVPQA PEFHPGGHAV IHRPPHPPLP
GFLPLPAMIP PPPRHIYSPV TGAGDMATQY IPQYHTSQMY GDLDTLPAHG RANFRDERSS
KTYERLQKKL KDRHGTQKDK LNSPPSSPQK CPSPTSEPNG LTKGQDTAGI STGSTKSKSV
GKGKSNSQTD VEIEEKDEET KALEALLSNI AKPVVSDVQA RTALLMWSPP SIDVGEDTDK
TNIPGVYTYE VMISNTGKDG KYKTVYIGEE NKVTVNDLRP ATDYHAKVQV ECNCVKGSPS
EVESFTTMSC EPDAPNLPRI TNRTKNSLTL QWKASCDNGS KIHSYLLEWD EGKGNGEFCQ
CYYGQQKQYR ITKLSPAMGY TFRLAAKNDM GMSGFSEEVL YHTSGTAATT PASPLLINAG
VTWLSLQWTK PSGTPSDEGI SYILEMEDEN SGYGFKPKYD GDDLTYTVKN LRRSTKYKFR
VIAYNSEGKS SPSETVDYTT CPDKPGAPSK PSVKGKIHAQ SFKIIWDPPK DNGGAAINTY
VVEISEGSNG NKWDTIYSGA AREHLCDRLN PGCSYRLRVY CIGEGGQSMA SDSLLVQTPA
VVPGPCQPPR LQGRPRAREI QLRWGPPQVD GGSPITCYGL EMFQTETDEH REVYQGSDVE
CTVGSLLPGR MYNFRLRAAN KAGFGPYSEK CEITTAPGPP DQCKPPQVTC RSAACAQVSW
EVPVSNGADV TEYRLEWGGM EGCMQISYCG PGLNCEMKGL LPATIYYCRV QAVNVAGAGP
FSEVVACMTP ASVPAVVTCL RGLSEDEVES PHYYPSTCLA LSWEKPCDHG SEITGYSIDF
GDKQPITVGK VLSYFIDGLQ PDTTYRIRIQ ALNSLGAGPF SHTIKLKTKP LPPDPPRLEC
VAYSSQTLKL KWGEGTAKAL TDSIQYHLQM EDKNGRFVSL YRGPCHTYKV QRLSESTSYK
FCIQACNEAG EGPLSQEYVF TTPKSVPAAL KAPRIERIND HTCEITWEVL QPMKGDPVIY
CLQVMVGKDS EFKQIYKGPD WSFRYTGLQL NCEYRFRACA IRQCQETSGH QDLIGPYSSP
VLFISQRTEP PTSTNKDTVQ TTRTQWSQSD QVCAAVILAL FAIFSILIAV IIQYFVIK
