FND_MYTCA
ID FND_MYTCA Reviewed; 225 AA.
AC P86861;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 08-FEB-2011, sequence version 1.
DT 03-AUG-2022, entry version 26.
DE RecName: Full=Fibronectin type III domain-containing protein;
DE AltName: Full=Fibronectin-like protein {ECO:0000303|PubMed:21643827};
DE Flags: Precursor; Fragment;
OS Mytilus californianus (California mussel).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Mytilida; Mytiloidea; Mytilidae; Mytilinae;
OC Mytilus.
OX NCBI_TaxID=6549;
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Gracey A., Grimwood J., Schmutz J., Myers R.M.;
RT "Expressed sequence tags from Mytilus californianus.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000305}
RP PROTEIN SEQUENCE OF 161-177, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC TISSUE=Shell {ECO:0000269|PubMed:21643827};
RX PubMed=21643827; DOI=10.1007/s00239-011-9451-6;
RA Marie B., Le Roy N., Zanella-Cleon I., Becchi M., Marin F.;
RT "Molecular evolution of mollusc shell proteins: insights from proteomic
RT analysis of the edible mussel mytilus.";
RL J. Mol. Evol. 72:531-546(2011).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21643827}.
CC -!- TISSUE SPECIFICITY: Component of the organic matrix of calcified shell
CC layers like nacre and prisms. {ECO:0000269|PubMed:21643827}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GE759315; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; P86861; -.
DR SMR; P86861; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR Pfam; PF00041; fn3; 1.
DR SMART; SM00060; FN3; 1.
DR SUPFAM; SSF49265; SSF49265; 1.
DR PROSITE; PS50853; FN3; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Secreted; Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..225
FT /note="Fibronectin type III domain-containing protein"
FT /evidence="ECO:0000255"
FT /id="PRO_0000404088"
FT DOMAIN 106..206
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT NON_TER 225
FT /evidence="ECO:0000303|PubMed:21643827"
SQ SEQUENCE 225 AA; 24832 MW; CFED3C0DA7E9EBC5 CRC64;
MFSFGIILLT VVSFTNAQWR QDMFTTAENQ LRSIVQNGQT LLDFIYQERQ KHGGGNMTGG
SLMSHNVAYS SFINDVETRL ADMEQATQEL VRIMRTCPDA PLAPPPPTNV IVESTTIDNV
SSIVVKWDPP FNPPENMQYK VYFVPVDQNG MQTAGEVVFR ICDSTQTIAS ITDLTPRSRY
RIRVGAVAGA VAEGASMPLN VKTPDIIPSR VRNVMVKSST ANTIT