FNRL_CERS4
ID FNRL_CERS4 Reviewed; 248 AA.
AC P51007; Q3J010;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=Transcriptional activator protein FnrL;
GN Name=fnrL; OrderedLocusNames=RHOS4_23060; ORFNames=RSP_0698;
OS Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS sphaeroides).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Cereibacter.
OX NCBI_TaxID=272943;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7592416; DOI=10.1128/jb.177.22.6422-6431.1995;
RA Zeilstra-Ryalls J.H., Kaplan S.;
RT "Aerobic and anaerobic regulation in Rhodobacter sphaeroides 2.4.1: the
RT role of the fnrL gene.";
RL J. Bacteriol. 177:6422-6431(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC / NCIMB 8253 / ATH 2.4.1.;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Anaerobic regulatory protein; transcriptional activator of
CC hemA. Appears to regulate other genes.
CC -!- MISCELLANEOUS: Possesses 4 cysteines which may bind a metal ion
CC (possibly iron).
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DR EMBL; Z49746; CAA89820.1; -; Genomic_DNA.
DR EMBL; CP000143; ABA79874.1; -; Genomic_DNA.
DR RefSeq; WP_002720880.1; NZ_CP030271.1.
DR RefSeq; YP_353775.1; NC_007493.2.
DR AlphaFoldDB; P51007; -.
DR SMR; P51007; -.
DR STRING; 272943.RSP_0698; -.
DR EnsemblBacteria; ABA79874; ABA79874; RSP_0698.
DR GeneID; 57471024; -.
DR KEGG; rsp:RSP_0698; -.
DR PATRIC; fig|272943.9.peg.2650; -.
DR eggNOG; COG0664; Bacteria.
DR OMA; IENNRHV; -.
DR PhylomeDB; P51007; -.
DR Proteomes; UP000002703; Chromosome 1.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 2.60.120.10; -; 1.
DR InterPro; IPR018490; cNMP-bd-like.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR018335; Tscrpt_reg_HTH_Crp-type_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR PRINTS; PR00034; HTHCRP.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF51206; SSF51206; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS00042; HTH_CRP_1; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Activator; DNA-binding; Iron; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..248
FT /note="Transcriptional activator protein FnrL"
FT /id="PRO_0000100180"
FT DOMAIN 154..232
FT /note="HTH crp-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00387"
FT DNA_BIND 191..210
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00387"
SQ SEQUENCE 248 AA; 27800 MW; 788F5BB365AE7DAD CRC64;
MTLHEVPTIL HRCGDCPIRH RAVCARCDSE ELATLEQIKY YRSYQAGQTV IWSGDKMDFV
ASVVTGIATL TQTMEDGRRQ MVGLLLPSDF VGRPGRQTVA YDVTATTDLL MCCFRRKPFE
EMMQKTPHVG QRLLEMTLDE LDAAREWMLL LGRKTAREKI ASLLAIIARR DAALKLRESN
GPMTFDLPLT REEMADYLGL TLETVSRQVS ALKRDGVIAL EGKRHVIVTD FARLLEEAGD
DSDGGLPV
