ID   FNRN_RHILV              Reviewed;         240 AA.
AC   P24290;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Probable transcriptional activator;
DE   AltName: Full=ORF-240;
GN   Name=fnrN;
OS   Rhizobium leguminosarum bv. viciae.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=387;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=VF39;
RX   PubMed=2175385; DOI=10.1007/bf00315806;
RA   Colonna-Romano S., Arnold W., Schlueter A., Boistard P., Puehler A.,
RA   Priefer U.B.;
RT   "An Fnr-like protein encoded in Rhizobium leguminosarum biovar viciae shows
RT   structural and functional homology to Rhizobium meliloti FixK.";
RL   Mol. Gen. Genet. 223:138-147(1990).
CC   -!- FUNCTION: Promotes the microaerobic and symbiotic induction of fixN,
CC       possibly by binding to the FNR consensus binding site upstream of fixN.
CC   -!- MISCELLANEOUS: Possesses 4 cysteines which may bind a metal ion
CC       (possibly iron).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X55788; CAA39312.1; -; Genomic_DNA.
DR   PIR; S11951; S11951.
DR   RefSeq; WP_011652344.1; NZ_WIEL01000004.1.
DR   AlphaFoldDB; P24290; -.
DR   SMR; P24290; -.
DR   OMA; QARDHMV; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR012318; HTH_CRP.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR018335; Tscrpt_reg_HTH_Crp-type_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF13545; HTH_Crp_2; 1.
DR   PRINTS; PR00034; HTHCRP.
DR   SMART; SM00100; cNMP; 1.
DR   SMART; SM00419; HTH_CRP; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00042; HTH_CRP_1; 1.
DR   PROSITE; PS51063; HTH_CRP_2; 1.
PE   4: Predicted;
KW   Activator; DNA-binding; Nitrogen fixation; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..240
FT                   /note="Probable transcriptional activator"
FT                   /id="PRO_0000100159"
FT   DOMAIN          158..232
FT                   /note="HTH crp-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00387"
FT   DNA_BIND        191..210
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00387"
FT   REGION          17..28
FT                   /note="Essential for the oxygen-regulated activity"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   240 AA;  26844 MW;  AE578D84EB30D657 CRC64;
     MDVARSEFFE TGTPVACTSC QARHGVVCGA LSKGQLRELN RHSLRRKIEA GCEIIAQGSE
     SSFYSNIMRG VMKLCKVMPD GRQQIVGLQF APDFVGRPFV RESTLSAEAA TDSEICVFPR
     NLLDRMISET PELQRSLHDQ ALKELDAARE WMLTLGRRTA EEKVASLLHL IATHAEPQTA
     TSTAFDLPLS RAEIADFLGL TIETVSRQMT RLRKIGVIRI ENFRHIIVPD MDELERMISA