009L_FRG3G
ID 009L_FRG3G Reviewed; 948 AA.
AC Q6GZW6;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Putative helicase 009L;
DE EC=3.6.4.-;
GN ORFNames=FV3-009L;
OS Frog virus 3 (isolate Goorha) (FV-3).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Iridoviridae; Alphairidovirinae; Ranavirus.
OX NCBI_TaxID=654924;
OH NCBI_TaxID=30343; Dryophytes versicolor (chameleon treefrog).
OH NCBI_TaxID=8404; Lithobates pipiens (Northern leopard frog) (Rana pipiens).
OH NCBI_TaxID=45438; Lithobates sylvaticus (Wood frog) (Rana sylvatica).
OH NCBI_TaxID=8316; Notophthalmus viridescens (Eastern newt) (Triturus viridescens).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15165820; DOI=10.1016/j.virol.2004.02.019;
RA Tan W.G., Barkman T.J., Gregory Chinchar V., Essani K.;
RT "Comparative genomic analyses of frog virus 3, type species of the genus
RT Ranavirus (family Iridoviridae).";
RL Virology 323:70-84(2004).
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DR EMBL; AY548484; AAT09668.1; -; Genomic_DNA.
DR RefSeq; YP_031587.1; NC_005946.1.
DR PRIDE; Q6GZW6; -.
DR GeneID; 2947781; -.
DR KEGG; vg:2947781; -.
DR Proteomes; UP000008770; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.10810; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT CHAIN 1..948
FT /note="Putative helicase 009L"
FT /id="PRO_0000410580"
FT DOMAIN 64..243
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 371..554
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT MOTIF 187..190
FT /note="DEAH box"
FT BINDING 77..84
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ SEQUENCE 948 AA; 106444 MW; FD4765111B43B4FF CRC64;
MDTSPYDFLK LYPWLSRGEA DKGTLLDAFP GETFEQSLAS DVAMRRAVQD DPAFGHQKLV
ETFLSEDTPY RELLLFHAPG TGKTCTVVSV AERAKEKGLT RGCIVLARGA ALLRNFLHEL
VFNCGTGGRY IPEGYADMGD QERTRKMRKA VSSYYQFRTY ETFAKSVATM SAEAIRARYD
RFVIVMDEVH HLRSVQAEGV NTYSAISRFL RTVRGCVKML LTGTPMTNEP GELADVLNLI
LPQDKTIRPE DGIFSNSGDL LKPDELAERV RGRVSYLKAA RPDAGLTFAG EVLGGTGMTH
LRLVRLEMSA FQSDAYASAW DQDAGDRNIF SNSRQCSLAV MPDRRWGSAA EARNPSQVRR
MAGQNLAEYS VKYDYLVRVA SSSPKTFAYC EYVNGSGLSL LSDILLANGW RRATGRETTP
GKRFALLTAS QKNIHKIVQR FNHEDNVDGA YISLLLGSRV VAEGLTFKEV RHTVILTPHW
NYTETAQAIA RSWRAGSHDR LKARGEAVAV TVHRLVAVPR GRDTPRSIDS DMYAVSEVKD
KRIKAVERIL MTSAADCSLL RSRNLYPSEF DGSRECEYGR CAYRCSNVSV EPGPLPALLG
ASAAEAVAQV RLDGGGDPAI MKVDMSTLWA EVTAGRRYVN RWGDGAVLRA EGGRLELSAP
YGSSEEGRWG DFYKTRNLCY AKMDQDHLRA DDLRDSLPQE VEELLTVSPV ETIGETASAM
PQEVATAILM ACVQARADGK TLNVVRRDAL LDFYKGFYAM GPSGWTVWLH ARGANAKVYD
GRRWNPADED TLEFLAARSA KFTDTRIGYY GLYNPNLKDF CIRDVTQGKR DKVDLRKLTV
GRRCVDWDQR TLVHIVARLM KIDGRRDFMP HATLREMREL AEQDPLHEPS DLTSKEACRR
FLFWTQKGDN KFRRQDICKA MEKWFIENDL MEDNFDCGHQ HKRRGKFA