ALAE_SODGM
ID ALAE_SODGM Reviewed; 126 AA.
AC Q2NVW1;
DT 22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT 07-FEB-2006, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=L-alanine exporter AlaE {ECO:0000255|HAMAP-Rule:MF_00914};
GN Name=alaE {ECO:0000255|HAMAP-Rule:MF_00914}; OrderedLocusNames=SG0439;
OS Sodalis glossinidius (strain morsitans).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=343509;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=morsitans;
RX PubMed=16365377; DOI=10.1101/gr.4106106;
RA Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA Aksoy S.;
RT "Massive genome erosion and functional adaptations provide insights into
RT the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL Genome Res. 16:149-156(2006).
CC -!- FUNCTION: Exports L-alanine. {ECO:0000255|HAMAP-Rule:MF_00914}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00914}; Single-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00914}.
CC -!- SIMILARITY: Belongs to the AlaE exporter family. {ECO:0000255|HAMAP-
CC Rule:MF_00914}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP008232; BAE73714.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2NVW1; -.
DR STRING; 343509.SG0439; -.
DR EnsemblBacteria; BAE73714; BAE73714; SG0439.
DR KEGG; sgl:SG0439; -.
DR eggNOG; ENOG502ZRFS; Bacteria.
DR HOGENOM; CLU_1980099_0_0_6; -.
DR Proteomes; UP000001932; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0034639; F:L-amino acid efflux transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032973; P:amino acid export across plasma membrane; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00914; L_Ala_exporter; 1.
DR InterPro; IPR010574; Ala_export_AlaE.
DR Pfam; PF06610; AlaE; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..126
FT /note="L-alanine exporter AlaE"
FT /id="PRO_0000415630"
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00914"
SQ SEQUENCE 126 AA; 14381 MW; B2B0E6D62FFAF9A8 CRC64;
MRWSCHPMSS VTSRLRSATA DTFALVVYCF FTGMAIEILL SGMSLQQSLS SRVLAIPVNV
IIAWPFGQYR DAVVSLASRH GPKQFWTRNL ADLLAMSVFN HRSMRRFFLR WGWSGGSCSR
RWSAMR