ID   FOCD_ECOLX              Reviewed;         875 AA.
AC   P46009;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Outer membrane usher protein FocD;
DE   Flags: Precursor;
GN   Name=focD;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AD110 / UPEC;
RX   PubMed=7836295; DOI=10.1128/jb.177.3.621-627.1995;
RA   Klemm P., Joergensen B.J., Kreft B., Christiansen G.;
RT   "The export systems of type 1 and F1C fimbriae are interchangeable but work
RT   in parental pairs.";
RL   J. Bacteriol. 177:621-627(1995).
CC   -!- FUNCTION: Involved in the export and assembly of the F1C fimbriae
CC       subunits across the outer membrane.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the fimbrial export usher family. {ECO:0000305}.
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DR   EMBL; Z46635; CAA86605.1; -; Genomic_DNA.
DR   PIR; S49608; S49608.
DR   AlphaFoldDB; P46009; -.
DR   SMR; P46009; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015473; F:fimbrial usher porin activity; IEA:InterPro.
DR   GO; GO:0009297; P:pilus assembly; IEA:InterPro.
DR   Gene3D; 2.60.40.2070; -; 1.
DR   Gene3D; 2.60.40.2610; -; 1.
DR   Gene3D; 3.10.20.410; -; 1.
DR   InterPro; IPR000015; Fimb_usher.
DR   InterPro; IPR018030; Fimbrial_membr_usher_CS.
DR   InterPro; IPR042186; FimD_plug_dom.
DR   InterPro; IPR025949; PapC-like_C.
DR   InterPro; IPR043142; PapC-like_C_sf.
DR   InterPro; IPR025885; PapC_N.
DR   InterPro; IPR037224; PapC_N_sf.
DR   PANTHER; PTHR30451; PTHR30451; 1.
DR   Pfam; PF13953; PapC_C; 1.
DR   Pfam; PF13954; PapC_N; 1.
DR   Pfam; PF00577; Usher; 1.
DR   SUPFAM; SSF141729; SSF141729; 1.
DR   PROSITE; PS01151; FIMBRIAL_USHER; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Disulfide bond; Fimbrium biogenesis; Membrane; Signal;
KW   Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..38
FT                   /evidence="ECO:0000255"
FT   CHAIN           39..875
FT                   /note="Outer membrane usher protein FocD"
FT                   /id="PRO_0000009315"
FT   DISULFID        852..874
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   875 AA;  96211 MW;  6D8B5C113D4255DF CRC64;
     MFFGDGGQLL SDKSLTGSAG GGNNRMKFNI LPLAFFIGII VSPARAELYF NRRFLSDDPD
     AVADLSAFTQ GQELPPGVYR VDIYLNDTYI STRDVQFQMS QDGKQLAPCL SPEHMSAMGV
     NRYAVPGMER LPADTCTSLN SMIQGATFRF DVGQQRLYLT VPQLYMSNQA RGYIAPEYWD
     NGITAALLNY DFSGNRVRDT YGGTSDYAYL NLKTGLNIGS WRLRDNTSWS YSAGKGYSQN
     NWQHINTWLE RDIVSLRSRL TMGDSYTRGD IFDGVNFRGI QLASDDNMVP DSQRGYAPTI
     HGISRGTSRI SIRQNGYEIY QSTLPPGPFE INDIYPAGSG GDLQVTLQEA DGSVQRFNVP
     WSSVPVLQRE GHLKYALSAG EFRSGGHQQD NPRFAEGTLK YGLPDGWTVY GGAWIAERYR
     AFNLGVGKNM GWLGAVSLDA TRANARLPDE SRHDGQSYRF LYNKSLTETG TNIQLIGYRY
     STRGYFTFAD TAWKKMSGYS VLTQDGVIQI QPKYTDYYNL AYNKREGAGE YQPADGESST
     LYLSGSHQSY WGTDRTDRQL NAGFNSSVND ISWSLNYSLS RNAWQHETDR ILSFDVSIPF
     SHWMRSDSTS AWRNASARYS QTLEAHGQAA STAGLYGTLL GDNNLGYSIQ SGYTRGGYEG
     SSKTGYASLN YRGGYGNASA GYSHSGGYRQ LYYGLSGGIL AHANGLTLSQ PLGDTLILVR
     APGASDTRIE NQTGVSTDWR GYAVLPYATD YRENRVALDT NTLADNVDIE NTVVSVVPTH
     GAVVRADYKT RVGVKVLMTL MRNGKAVPFG SVVTARNGGS SIAGENGQVY LSGMPLSGQV
     SVKWGSQTTD QCTADYKLPK ESAGQILSHV TASCR