ID   ALB1_LUPAN              Reviewed;          81 AA.
AC   Q96474;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Albumin-1;
DE            Short=A1;
DE   Contains:
DE     RecName: Full=Albumin-1 chain b;
DE              Short=A1b;
DE     AltName: Full=Leginsulin;
DE   Contains:
DE     RecName: Full=Albumin-1 chain a;
DE              Short=A1a;
DE   Flags: Precursor; Fragment;
GN   Name=LEG1;
OS   Lupinus angustifolius (Narrow-leaved blue lupine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   genistoids sensu lato; core genistoids; Genisteae; Lupinus.
OX   NCBI_TaxID=3871;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Unicrop;
RX   PubMed=9247543; DOI=10.1023/a:1005868105651;
RA   Ilgoutz S.C., Knittel N., Lin J.M., Sterle S., Gayler K.R.;
RT   "Transcription of genes for conglutin gamma and a leginsulin-like protein
RT   in narrow-leafed lupin.";
RL   Plant Mol. Biol. 34:613-627(1997).
CC   -!- FUNCTION: A1b binds to basic 7S globulin (BG) and stimulates its
CC       phosphorylation activity. {ECO:0000250}.
CC   -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC       structurally defines this protein as a knottin. {ECO:0000250}.
CC   -!- PTM: Three disulfide bonds are probably present.
CC   -!- PTM: The C-terminal glycine may be removed from A1b.
CC   -!- CAUTION: While it is structurally defined as a knottin it lacks the
CC       conserved Cys residue in position 4. {ECO:0000305}.
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DR   EMBL; U74383; AAC49786.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q96474; -.
DR   SMR; Q96474; -.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   InterPro; IPR012512; Albumin_I.
DR   InterPro; IPR032000; Albumin_I_a.
DR   Pfam; PF08027; Albumin_I; 1.
DR   Pfam; PF16720; Albumin_I_a; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Knottin; Seed storage protein; Storage protein; Toxin.
FT   CHAIN           <1..26
FT                   /note="Albumin-1 chain b"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000032243"
FT   PROPEP          27..34
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000032244"
FT   CHAIN           35..>81
FT                   /note="Albumin-1 chain a"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000032245"
FT   NON_TER         1
FT   NON_TER         81
SQ   SEQUENCE   81 AA;  8908 MW;  70014D8E9BBF5439 CRC64;
     IPPSRSSDCR CVPITLIVGF CIHPTGLSSV AKMIDEHPNL CQSDDECMKK GSGNFCARYP
     NNYIDYGWCF GSDSEALKGF L