ALB33_ARATH
ID ALB33_ARATH Reviewed; 566 AA.
AC Q0WUC5; Q7XJ56; Q9M288; Q9M289;
DT 18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=ALBINO3-like protein 3, mitochondrial;
DE Flags: Precursor;
GN Name=ALB3L3; OrderedLocusNames=At3g44370/At3g44360;
GN ORFNames=T22K7_50/T22K7_40;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 423-566.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND CLEAVAGE OF TRANSIT PEPTIDE AFTER
RP PHE-44.
RX PubMed=25732537; DOI=10.1093/jxb/erv064;
RA Carrie C., Venne A.S., Zahedi R.P., Soll J.;
RT "Identification of cleavage sites and substrate proteins for two
RT mitochondrial intermediate peptidases in Arabidopsis thaliana.";
RL J. Exp. Bot. 66:2691-2708(2015).
CC -!- FUNCTION: Probably required for the insertion of integral membrane
CC proteins into the mitochondrial inner membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000305|PubMed:25732537}; Multi-pass membrane protein
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC (TC 2.A.9.2) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB86914.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes At3g44360 and At3g44370.; Evidence={ECO:0000305};
CC Sequence=CAB86915.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes At3g44360 and At3g44370.; Evidence={ECO:0000305};
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DR EMBL; AL138641; CAB86914.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL138641; CAB86915.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77897.1; -; Genomic_DNA.
DR EMBL; AK227236; BAE99273.1; -; mRNA.
DR EMBL; BT009724; AAP88358.1; -; mRNA.
DR PIR; T47426; T47426.
DR PIR; T47427; T47427.
DR RefSeq; NP_190023.2; NM_114305.4.
DR AlphaFoldDB; Q0WUC5; -.
DR SMR; Q0WUC5; -.
DR STRING; 3702.AT3G44370.1; -.
DR PaxDb; Q0WUC5; -.
DR PRIDE; Q0WUC5; -.
DR ProteomicsDB; 245013; -.
DR EnsemblPlants; AT3G44370.1; AT3G44370.1; AT3G44370.
DR GeneID; 823562; -.
DR Gramene; AT3G44370.1; AT3G44370.1; AT3G44370.
DR KEGG; ath:AT3G44370; -.
DR Araport; AT3G44370; -.
DR TAIR; locus:2100172; AT3G44370.
DR eggNOG; KOG1239; Eukaryota.
DR HOGENOM; CLU_032608_1_0_1; -.
DR InParanoid; Q0WUC5; -.
DR OrthoDB; 1314061at2759; -.
DR PhylomeDB; Q0WUC5; -.
DR PRO; PR:Q0WUC5; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q0WUC5; baseline and differential.
DR Genevisible; Q0WUC5; AT.
DR GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0032977; F:membrane insertase activity; IBA:GO_Central.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IMP:TAIR.
DR GO; GO:0051205; P:protein insertion into membrane; IMP:TAIR.
DR GO; GO:0032979; P:protein insertion into mitochondrial inner membrane from matrix; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR PANTHER; PTHR12428; PTHR12428; 1.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 1: Evidence at protein level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; TPR repeat; Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..44
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:25732537"
FT CHAIN 45..566
FT /note="ALBINO3-like protein 3, mitochondrial"
FT /id="PRO_0000416825"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 207..227
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 386..419
FT /note="TPR 1"
FT REPEAT 420..453
FT /note="TPR 2"
FT REPEAT 465..498
FT /note="TPR 3"
FT REPEAT 507..540
FT /note="TPR 4"
FT REGION 547..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 62798 MW; 544D6CBC1EB312DE CRC64;
MAFRRVLLSH LRRSHHTCSS LSPHHVSATT QPSIALALFQ SRFFSTPSDL DSELTRFRDD
SIAGVGSNDH GLEFDDSIAS LGSNGHGLEF GDSIGSLGSN GYGLEFGDLS QDLSNYDYLT
QPVISLLDSY HDITGLPWWV VIATSTVAFR TALLPILILQ RKQTKRISQF LPKLPHFWPP
QGSGRSVLDQ LKLFRKERKD IGCPSFLWVP AYFSIQISCF FLWITSIRRM SLDHHPGFDS
GGALWFQNLT EIPNGLYGPL FPFLIAGLHY TNTQITFTAS SVHKVDKFTE LAKAYKTFLN
LLTCALYFLS FQMPQGSLLY WATNLSFSIA QQSILNHPVV SAKLGLQAND SVQKEAGNPI
LTNINEGKLT DPSSKGRLIS VHNLTPKELV ALSAKYLSGG HKDKSIPLLR LALEKDPEYL
QAMIILGQAL YQKDQFAEAA KCLEQAASKL LDTSPTEVEE VDLLIVASQW AGVSNIRQGK
TSEGITHLER VANMKEPDDP KSKAHYLDAL VLYSSAIFNE GRREEAAKYL RRVVAYDPSF
SELLKQCEED DTIPTSSSSN STSKTS
