ID   ALBA2_AERPE             Reviewed;         102 AA.
AC   Q9YAX2;
DT   09-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=DNA/RNA-binding protein Alba 2;
GN   Name=albA2; OrderedLocusNames=APE_1823;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- FUNCTION: Binds double-stranded DNA tightly but without sequence
CC       specificity. It is distributed uniformly and abundantly on the
CC       chromosome, suggesting a role in chromatin architecture. However, it
CC       does not significantly compact DNA. Binds rRNA and mRNA in vivo. May
CC       play a role in maintaining the structural and functional stability of
CC       RNA, and, perhaps, ribosomes (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Chromosome
CC       {ECO:0000250}.
CC   -!- PTM: Acetylated. Deacetylation by the SIR2-homolog deacetylase may
CC       regulate its activity (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the histone-like Alba family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000002; BAA80826.1; -; Genomic_DNA.
DR   PIR; E72567; E72567.
DR   PDB; 2H9U; X-ray; 2.00 A; A=1-102.
DR   PDB; 3U6Y; X-ray; 2.00 A; A/C=1-102.
DR   PDBsum; 2H9U; -.
DR   PDBsum; 3U6Y; -.
DR   AlphaFoldDB; Q9YAX2; -.
DR   SMR; Q9YAX2; -.
DR   STRING; 272557.APE_1823; -.
DR   EnsemblBacteria; BAA80826; BAA80826; APE_1823.
DR   KEGG; ape:APE_1823; -.
DR   eggNOG; arCOG01753; Archaea.
DR   OMA; QFNEGAK; -.
DR   EvolutionaryTrace; Q9YAX2; -.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.110.20; -; 1.
DR   HAMAP; MF_01122; AlbA; 1.
DR   InterPro; IPR036882; Alba-like_dom_sf.
DR   InterPro; IPR013795; DNA/RNA-bd_Alba.
DR   InterPro; IPR002775; DNA/RNA-bd_Alba-like.
DR   Pfam; PF01918; Alba; 1.
DR   PIRSF; PIRSF028732; Alba; 1.
DR   SUPFAM; SSF82704; SSF82704; 1.
DR   TIGRFAMs; TIGR00285; TIGR00285; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acetylation; Chromosome; Cytoplasm; DNA-binding;
KW   Reference proteome; RNA-binding.
FT   CHAIN           1..102
FT                   /note="DNA/RNA-binding protein Alba 2"
FT                   /id="PRO_0000151695"
FT   MOD_RES         14
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250"
FT   STRAND          8..10
FT                   /evidence="ECO:0007829|PDB:2H9U"
FT   HELIX           16..27
FT                   /evidence="ECO:0007829|PDB:2H9U"
FT   STRAND          34..40
FT                   /evidence="ECO:0007829|PDB:2H9U"
FT   HELIX           43..57
FT                   /evidence="ECO:0007829|PDB:2H9U"
FT   TURN            58..61
FT                   /evidence="ECO:0007829|PDB:2H9U"
FT   STRAND          62..77
FT                   /evidence="ECO:0007829|PDB:2H9U"
FT   STRAND          79..81
FT                   /evidence="ECO:0007829|PDB:3U6Y"
FT   STRAND          83..97
FT                   /evidence="ECO:0007829|PDB:2H9U"
SQ   SEQUENCE   102 AA;  11380 MW;  F3F5103D9E775D10 CRC64;
     MACEGAPEVR IGRKPVMNYV LAILTTLMEQ GTNQVVVKAR GRNINRAVDA VEIVRKRFAK
     NIEIKDIKID SQEIEVQTPE GQTRTRRVSS IEICLEKAGE SA