ID   3MGH_STAA1              Reviewed;         202 AA.
AC   A7X5V7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=SAHV_2328;
OS   Staphylococcus aureus (strain Mu3 / ATCC 700698).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=418127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu3 / ATCC 700698;
RX   PubMed=17954695; DOI=10.1128/aac.00534-07;
RA   Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.;
RT   "Mutated response regulator graR is responsible for phenotypic conversion
RT   of Staphylococcus aureus from heterogeneous vancomycin-intermediate
RT   resistance to vancomycin-intermediate resistance.";
RL   Antimicrob. Agents Chemother. 52:45-53(2008).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; AP009324; BAF79211.1; -; Genomic_DNA.
DR   RefSeq; WP_000348300.1; NZ_CTYB01000041.1.
DR   AlphaFoldDB; A7X5V7; -.
DR   SMR; A7X5V7; -.
DR   KEGG; saw:SAHV_2328; -.
DR   HOGENOM; CLU_060471_2_0_9; -.
DR   OMA; VEAYHHT; -.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..202
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_1000051000"
SQ   SEQUENCE   202 AA;  22771 MW;  231650C02B31F4E1 CRC64;
     MDFVNNDTRQ IAKNLLGVKV IYQDTTQTYT GYIVETEAYL GLNDRAAHGY GGKITPKVTS
     LYKRGGTIYA HVMHTHLLIN FVTKSEGIPE GVLIRAIEPE EGLSAMFRNR GKKGYEVTNG
     PGKWTKAFNI PRAIDGATLN DCRLSIDTKN RKYPKDIIAS PRIGIPNKGD WTHKSLRYTV
     KGNPFVSRMR KSDCMFPEDT WK