ID   ALBA2_SACSH             Reviewed;          89 AA.
AC   P74762;
DT   09-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=DNA/RNA-binding protein Alba 2;
GN   Name=albA2;
OS   Saccharolobus shibatae (Sulfolobus shibatae).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=2286;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 51178 / DSM 5389 / JCM 8931 / NBRC 15437 / B12;
RX   PubMed=8972852; DOI=10.1093/nar/24.23.4668;
RA   Jaxel C., Bouthier de la Tour C., Duguet M., Nadal M.;
RT   "Reverse gyrase gene from Sulfolobus shibatae B12: gene structure,
RT   transcription unit and comparative sequence analysis of the two domains.";
RL   Nucleic Acids Res. 24:4668-4675(1996).
CC   -!- FUNCTION: Binds double-stranded DNA tightly but without sequence
CC       specificity. It is distributed uniformly and abundantly on the
CC       chromosome, suggesting a role in chromatin architecture. However, it
CC       does not significantly compact DNA. Binds rRNA and mRNA in vivo. May
CC       play a role in maintaining the structural and functional stability of
CC       RNA, and, perhaps, ribosomes (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Chromosome
CC       {ECO:0000250}.
CC   -!- PTM: Acetylated. Deacetylation by the SIR2-homolog deacetylase may
CC       regulate its activity (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the histone-like Alba family. {ECO:0000305}.
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DR   EMBL; X98420; CAA67067.1; -; Genomic_DNA.
DR   PIR; T29102; T29102.
DR   RefSeq; WP_012711268.1; NZ_CP077715.1.
DR   AlphaFoldDB; P74762; -.
DR   BMRB; P74762; -.
DR   SMR; P74762; -.
DR   GeneID; 8761189; -.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.110.20; -; 1.
DR   HAMAP; MF_01122; AlbA; 1.
DR   InterPro; IPR036882; Alba-like_dom_sf.
DR   InterPro; IPR013795; DNA/RNA-bd_Alba.
DR   InterPro; IPR002775; DNA/RNA-bd_Alba-like.
DR   Pfam; PF01918; Alba; 1.
DR   PIRSF; PIRSF028732; Alba; 1.
DR   SUPFAM; SSF82704; SSF82704; 1.
PE   3: Inferred from homology;
KW   Acetylation; Chromosome; Cytoplasm; DNA-binding; RNA-binding.
FT   CHAIN           1..89
FT                   /note="DNA/RNA-binding protein Alba 2"
FT                   /id="PRO_0000151710"
FT   MOD_RES         14
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   89 AA;  10265 MW;  A945AC40FB027F2B CRC64;
     MTEKLNEIVV RKTKNVEDHV LDVIVLFNQG IDEVILKGIG REISKAVDVY NSLKDRLGDG
     IQLVNVQTGS EVRDRRRISY ILLRLKRVY