ID   ALBA_METJA              Reviewed;          87 AA.
AC   Q57665;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=DNA/RNA-binding protein Alba {ECO:0000255|HAMAP-Rule:MF_01122};
GN   Name=albA {ECO:0000255|HAMAP-Rule:MF_01122}; OrderedLocusNames=MJ0212;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: Binds double-stranded DNA tightly but without sequence
CC       specificity. It is distributed uniformly and abundantly on the
CC       chromosome, suggesting a role in chromatin architecture. However, it
CC       does not significantly compact DNA. Binds rRNA and mRNA in vivo. May
CC       play a role in maintaining the structural and functional stability of
CC       RNA, and, perhaps, ribosomes. {ECO:0000255|HAMAP-Rule:MF_01122}.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_01122}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01122}.
CC       Chromosome {ECO:0000255|HAMAP-Rule:MF_01122}.
CC   -!- PTM: Acetylated. Deacetylation by the SIR2-homolog deacetylase may
CC       regulate its activity. {ECO:0000255|HAMAP-Rule:MF_01122}.
CC   -!- SIMILARITY: Belongs to the histone-like Alba family.
CC       {ECO:0000255|HAMAP-Rule:MF_01122}.
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DR   EMBL; L77117; AAB98197.1; -; Genomic_DNA.
DR   PIR; E64326; E64326.
DR   RefSeq; WP_010869708.1; NC_000909.1.
DR   PDB; 1NH9; X-ray; 2.00 A; A=1-87.
DR   PDBsum; 1NH9; -.
DR   AlphaFoldDB; Q57665; -.
DR   SMR; Q57665; -.
DR   STRING; 243232.MJ_0212; -.
DR   EnsemblBacteria; AAB98197; AAB98197; MJ_0212.
DR   GeneID; 1451062; -.
DR   KEGG; mja:MJ_0212; -.
DR   eggNOG; arCOG01753; Archaea.
DR   HOGENOM; CLU_110989_1_0_2; -.
DR   InParanoid; Q57665; -.
DR   OMA; QFNEGAK; -.
DR   OrthoDB; 111461at2157; -.
DR   PhylomeDB; Q57665; -.
DR   EvolutionaryTrace; Q57665; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   Gene3D; 3.30.110.20; -; 1.
DR   HAMAP; MF_01122; AlbA; 1.
DR   InterPro; IPR036882; Alba-like_dom_sf.
DR   InterPro; IPR013795; DNA/RNA-bd_Alba.
DR   InterPro; IPR002775; DNA/RNA-bd_Alba-like.
DR   Pfam; PF01918; Alba; 1.
DR   PIRSF; PIRSF028732; Alba; 1.
DR   SUPFAM; SSF82704; SSF82704; 1.
DR   TIGRFAMs; TIGR00285; TIGR00285; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acetylation; Chromosome; Cytoplasm; DNA-binding;
KW   Reference proteome; RNA-binding.
FT   CHAIN           1..87
FT                   /note="DNA/RNA-binding protein Alba"
FT                   /id="PRO_0000151698"
FT   MOD_RES         10
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01122"
FT   STRAND          3..7
FT                   /evidence="ECO:0007829|PDB:1NH9"
FT   HELIX           12..25
FT                   /evidence="ECO:0007829|PDB:1NH9"
FT   STRAND          27..34
FT                   /evidence="ECO:0007829|PDB:1NH9"
FT   HELIX           35..37
FT                   /evidence="ECO:0007829|PDB:1NH9"
FT   HELIX           38..51
FT                   /evidence="ECO:0007829|PDB:1NH9"
FT   STRAND          57..66
FT                   /evidence="ECO:0007829|PDB:1NH9"
FT   STRAND          78..86
FT                   /evidence="ECO:0007829|PDB:1NH9"
SQ   SEQUENCE   87 AA;  9675 MW;  50B16E3E9D2DB157 CRC64;
     MDNVVLIGKK PVMNYVVAVL TQLTSNDEVI IKARGKAINK AVDVAEMIRN RFIKDIKIKK
     IEIGTDKVKN PDGREVNVST IEIVLAK