FON1_ORYSJ
ID FON1_ORYSJ Reviewed; 994 AA.
AC Q5Z9N5; A0A0P0X1D4; A3BFF7; Q8SB35;
DT 03-APR-2013, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Leucine-rich repeat receptor-like kinase protein FLORAL ORGAN NUMBER1;
DE Short=OsFON1;
DE EC=2.7.11.1;
DE AltName: Full=CLV1-like LRR receptor kinase;
DE Flags: Precursor;
GN Name=FON1; OrderedLocusNames=Os06g0717200, LOC_Os06g50340;
GN ORFNames=OJ1540_H01.10, OsJ_22674, P0481E08.42, P0541C02.9;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, MUTAGENESIS OF GLY-205
RP AND PRO-903, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=15509765; DOI=10.1242/dev.01441;
RA Suzaki T., Sato M., Ashikari M., Miyoshi M., Nagato Y., Hirano H.Y.;
RT "The gene FLORAL ORGAN NUMBER1 regulates floral meristem size in rice and
RT encodes a leucine-rich repeat receptor kinase orthologous to Arabidopsis
RT CLAVATA1.";
RL Development 131:5649-5657(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP DISRUPTION PHENOTYPE.
RX PubMed=16511358;
RA Moon S., Jung K.H., Lee D.E., Lee D.Y., Lee J., An K., Kang H.G., An G.;
RT "The rice FON1 gene controls vegetative and reproductive development by
RT regulating shoot apical meristem size.";
RL Mol. Cells 21:147-152(2006).
CC -!- FUNCTION: Receptor-like kinase protein that regulates the size of the
CC floral meristem. {ECO:0000269|PubMed:15509765}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1;
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in shoot apical meristem, and after
CC transition to the reproductive phase, detected in the inflorescence and
CC the floral meristems. Expressed uniformly throughout the meristems.
CC Expressed also in floral organ primordia, such as the palea, lemma,
CC lodicules, stamens, carpels and ovules. {ECO:0000269|PubMed:15509765}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the floral meristem even after the
CC initiation of carpel primordia. {ECO:0000269|PubMed:15509765}.
CC -!- DISRUPTION PHENOTYPE: Semi-dwarf with altered numbers of floral organs
CC and rachis branches. Reduced number of tillers.
CC {ECO:0000269|PubMed:16511358}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAZ38296.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB182388; BAD82811.1; -; mRNA.
DR EMBL; AB182389; BAD82812.1; -; Genomic_DNA.
DR EMBL; AC091774; AAL79717.1; -; Genomic_DNA.
DR EMBL; AP003614; BAD53588.1; -; Genomic_DNA.
DR EMBL; AP003769; BAD61718.1; -; Genomic_DNA.
DR EMBL; AP008212; BAF20507.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS99515.1; -; Genomic_DNA.
DR EMBL; CM000143; EAZ38296.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_015642501.1; XM_015787015.1.
DR AlphaFoldDB; Q5Z9N5; -.
DR SMR; Q5Z9N5; -.
DR STRING; 4530.OS06T0717200-01; -.
DR PaxDb; Q5Z9N5; -.
DR PRIDE; Q5Z9N5; -.
DR EnsemblPlants; Os06t0717200-01; Os06t0717200-01; Os06g0717200.
DR GeneID; 4342080; -.
DR Gramene; Os06t0717200-01; Os06t0717200-01; Os06g0717200.
DR KEGG; osa:4342080; -.
DR eggNOG; ENOG502QQ4T; Eukaryota.
DR HOGENOM; CLU_000288_22_1_1; -.
DR InParanoid; Q5Z9N5; -.
DR OMA; GQFMVFN; -.
DR OrthoDB; 826997at2759; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000007752; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR Genevisible; Q5Z9N5; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0033612; F:receptor serine/threonine kinase binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR GO; GO:0010080; P:regulation of floral meristem growth; IMP:Gramene.
DR GO; GO:0048833; P:specification of floral organ number; IMP:Gramene.
DR Gene3D; 3.80.10.10; -; 4.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Developmental protein; Differentiation; Glycoprotein; Kinase;
KW Leucine-rich repeat; Membrane; Nucleotide-binding; Receptor;
KW Reference proteome; Repeat; Serine/threonine-protein kinase; Signal;
KW Transferase; Transmembrane; Transmembrane helix.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..994
FT /note="Leucine-rich repeat receptor-like kinase protein
FT FLORAL ORGAN NUMBER1"
FT /id="PRO_0000422041"
FT TRANSMEM 647..667
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 73..93
FT /note="LRR 1"
FT REPEAT 94..117
FT /note="LRR 2"
FT REPEAT 118..141
FT /note="LRR 3"
FT REPEAT 147..171
FT /note="LRR 4"
FT REPEAT 172..194
FT /note="LRR 5"
FT REPEAT 195..219
FT /note="LRR 6"
FT REPEAT 244..268
FT /note="LRR 7"
FT REPEAT 269..292
FT /note="LRR 8"
FT REPEAT 293..316
FT /note="LRR 9"
FT REPEAT 318..340
FT /note="LRR 10"
FT REPEAT 341..364
FT /note="LRR 11"
FT REPEAT 365..388
FT /note="LRR 12"
FT REPEAT 390..412
FT /note="LRR 13"
FT REPEAT 413..436
FT /note="LRR 14"
FT REPEAT 438..459
FT /note="LRR 15"
FT REPEAT 460..483
FT /note="LRR 16"
FT REPEAT 484..507
FT /note="LRR 17"
FT REPEAT 509..531
FT /note="LRR 18"
FT REPEAT 533..555
FT /note="LRR 19"
FT REPEAT 556..579
FT /note="LRR 20"
FT REPEAT 581..604
FT /note="LRR 21"
FT DOMAIN 704..978
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT ACT_SITE 828
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 710..718
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 731
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT CARBOHYD 75
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 98
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 124
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 129
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 159
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 256
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 315
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 352
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 495
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 509
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 514
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 562
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 578
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 606
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT MUTAGEN 205
FT /note="G->S: In fon1-2; enlargment of the floral meristem
FT and increased number of floral organs."
FT /evidence="ECO:0000269|PubMed:15509765"
FT MUTAGEN 903
FT /note="P->L: In fon1-1; enlargment of the floral meristem
FT and increased number of floral organs."
FT /evidence="ECO:0000269|PubMed:15509765"
SQ SEQUENCE 994 AA; 105512 MW; D331FEEE6618770C CRC64;
MPPTLLLLLL LLPPSLASPD RDIYALAKLK AALVPSPSAT APPPLADWDP AATSPAHCTF
SGVTCDGRSR VVAINLTALP LHSGYLPPEI ALLDSLANLT IAACCLPGHV PLELPTLPSL
RHLNLSNNNL SGHFPVPDSG GGASPYFPSL ELIDAYNNNL SGLLPPFSAS HARLRYLHLG
GNYFTGAIPD SYGDLAALEY LGLNGNTLSG HVPVSLSRLT RLREMYIGYY NQYDGGVPPE
FGDLGALLRL DMSSCNLTGP VPPELGRLQR LDTLFLQWNR LSGEIPPQLG DLSSLASLDL
SVNDLAGEIP PSLANLSNLK LLNLFRNHLR GSIPDFVAGF AQLEVLQLWD NNLTGNIPAG
LGKNGRLKTL DLATNHLTGP IPADLCAGRR LEMLVLMENG LFGPIPDSLG DCKTLTRVRL
AKNFLTGPVP AGLFNLPQAN MVELTDNLLT GELPDVIGGD KIGMLLLGNN GIGGRIPPAI
GNLPALQTLS LESNNFSGAL PPEIGNLKNL SRLNVSGNAL TGAIPDELIR CASLAAVDLS
RNGFSGEIPE SITSLKILCT LNVSRNRLTG ELPPEMSNMT SLTTLDVSYN SLSGPVPMQG
QFLVFNESSF VGNPGLCGGP VADACPPSMA GGGGGAGSQL RLRWDSKKML VALVAAFAAV
AVAFLGARKG CSAWRSAARR RSGAWKMTAF QKLEFSAEDV VECVKEDNII GKGGAGIVYH
GVTRGAELAI KRLVGRGGGE HDRGFSAEVT TLGRIRHRNI VRLLGFVSNR ETNLLLYEYM
PNGSLGEMLH GGKGGHLGWE ARARVAAEAA CGLCYLHHDC APRIIHRDVK SNNILLDSAF
EAHVADFGLA KFLGGATSEC MSAIAGSYGY IAPEYAYTLR VDEKSDVYSF GVVLLELITG
RRPVGGFGDG VDIVHWVRKV TAELPDNSDT AAVLAVADRR LTPEPVALMV NLYKVAMACV
EEASTARPTM REVVHMLSNP NSAQPNSGDL LVTF
