ID   3MGH_STAA8              Reviewed;         202 AA.
AC   Q2FVS1;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=SAOUHSC_02621;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000253; ABD31630.1; -; Genomic_DNA.
DR   RefSeq; WP_000348300.1; NZ_LS483365.1.
DR   RefSeq; YP_501082.1; NC_007795.1.
DR   AlphaFoldDB; Q2FVS1; -.
DR   SMR; Q2FVS1; -.
DR   STRING; 1280.SAXN108_2594; -.
DR   EnsemblBacteria; ABD31630; ABD31630; SAOUHSC_02621.
DR   GeneID; 3921398; -.
DR   KEGG; sao:SAOUHSC_02621; -.
DR   PATRIC; fig|93061.5.peg.2370; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_2_0_9; -.
DR   OMA; VEAYHHT; -.
DR   PRO; PR:Q2FVS1; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IBA:GO_Central.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..202
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265061"
SQ   SEQUENCE   202 AA;  22771 MW;  231650C02B31F4E1 CRC64;
     MDFVNNDTRQ IAKNLLGVKV IYQDTTQTYT GYIVETEAYL GLNDRAAHGY GGKITPKVTS
     LYKRGGTIYA HVMHTHLLIN FVTKSEGIPE GVLIRAIEPE EGLSAMFRNR GKKGYEVTNG
     PGKWTKAFNI PRAIDGATLN DCRLSIDTKN RKYPKDIIAS PRIGIPNKGD WTHKSLRYTV
     KGNPFVSRMR KSDCMFPEDT WK