ID   ALBA_THEVO              Reviewed;          89 AA.
AC   Q979S5;
DT   09-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=DNA/RNA-binding protein Alba {ECO:0000255|HAMAP-Rule:MF_01122};
GN   Name=albA {ECO:0000255|HAMAP-Rule:MF_01122}; OrderedLocusNames=TV1085;
GN   ORFNames=TVG1115434;
OS   Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
OS   15438 / GSS1).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1;
RX   PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA   Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y.,
RA   Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T.,
RA   Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT   "Archaeal adaptation to higher temperatures revealed by genomic sequence of
RT   Thermoplasma volcanium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
CC   -!- FUNCTION: Binds double-stranded DNA tightly but without sequence
CC       specificity. It is distributed uniformly and abundantly on the
CC       chromosome, suggesting a role in chromatin architecture. However, it
CC       does not significantly compact DNA. Binds rRNA and mRNA in vivo. May
CC       play a role in maintaining the structural and functional stability of
CC       RNA, and, perhaps, ribosomes. {ECO:0000255|HAMAP-Rule:MF_01122}.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_01122}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01122}.
CC       Chromosome {ECO:0000255|HAMAP-Rule:MF_01122}.
CC   -!- PTM: Acetylated. Deacetylation by the SIR2-homolog deacetylase may
CC       regulate its activity. {ECO:0000255|HAMAP-Rule:MF_01122}.
CC   -!- SIMILARITY: Belongs to the histone-like Alba family.
CC       {ECO:0000255|HAMAP-Rule:MF_01122}.
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DR   EMBL; BA000011; BAB60227.1; -; Genomic_DNA.
DR   RefSeq; WP_010917316.1; NC_002689.2.
DR   PDB; 4Z9E; X-ray; 2.49 A; A/B/C/D=1-89.
DR   PDBsum; 4Z9E; -.
DR   AlphaFoldDB; Q979S5; -.
DR   SMR; Q979S5; -.
DR   STRING; 273116.14325323; -.
DR   EnsemblBacteria; BAB60227; BAB60227; BAB60227.
DR   GeneID; 1441198; -.
DR   KEGG; tvo:TVG1115434; -.
DR   eggNOG; arCOG01753; Archaea.
DR   HOGENOM; CLU_110989_1_0_2; -.
DR   OMA; ITRHKFI; -.
DR   OrthoDB; 111461at2157; -.
DR   PhylomeDB; Q979S5; -.
DR   Proteomes; UP000001017; Chromosome.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.110.20; -; 1.
DR   HAMAP; MF_01122; AlbA; 1.
DR   InterPro; IPR036882; Alba-like_dom_sf.
DR   InterPro; IPR013795; DNA/RNA-bd_Alba.
DR   InterPro; IPR002775; DNA/RNA-bd_Alba-like.
DR   Pfam; PF01918; Alba; 1.
DR   PIRSF; PIRSF028732; Alba; 1.
DR   SUPFAM; SSF82704; SSF82704; 1.
DR   TIGRFAMs; TIGR00285; TIGR00285; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acetylation; Chromosome; Cytoplasm; DNA-binding; RNA-binding.
FT   CHAIN           1..89
FT                   /note="DNA/RNA-binding protein Alba"
FT                   /id="PRO_0000151717"
FT   MOD_RES         12
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01122"
FT   STRAND          6..8
FT                   /evidence="ECO:0007829|PDB:4Z9E"
FT   HELIX           14..25
FT                   /evidence="ECO:0007829|PDB:4Z9E"
FT   TURN            26..28
FT                   /evidence="ECO:0007829|PDB:4Z9E"
FT   STRAND          30..37
FT                   /evidence="ECO:0007829|PDB:4Z9E"
FT   HELIX           38..40
FT                   /evidence="ECO:0007829|PDB:4Z9E"
FT   HELIX           41..54
FT                   /evidence="ECO:0007829|PDB:4Z9E"
FT   STRAND          60..69
FT                   /evidence="ECO:0007829|PDB:4Z9E"
FT   STRAND          80..88
FT                   /evidence="ECO:0007829|PDB:4Z9E"
SQ   SEQUENCE   89 AA;  9966 MW;  067DFE3A27A3FAB9 CRC64;
     MAEENIIFVG KKPTMNYVLA VVTQFNNNAN KIIIKARGKT ISKAVDVAEI TRHKFIPDAK
     YEEIRLDTET LQGERGSSNV SSIEITLSR