ID   ALBB_BACSU              Reviewed;          53 AA.
AC   P71010;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Antilisterial bacteriocin subtilosin biosynthesis protein AlbB;
GN   Name=albB; Synonyms=ywhR; OrderedLocusNames=BSU37380;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 6633 / PCI 219 / NRS 231;
RA   Stein T., Duesterhus S., Entian K.-D.;
RT   "Subtilosin A biosynthesis is conserved among two different classes of
RT   Bacillus subtilis strains.";
RL   Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9353933; DOI=10.1099/00221287-143-10-3313;
RA   Presecan E., Moszer I., Boursier L., Cruz Ramos H., De La Fuente V.,
RA   Hullo M.-F., Lelong C., Schleich S., Sekowska A., Song B.H., Villani G.,
RA   Kunst F., Danchin A., Glaser P.;
RT   "The Bacillus subtilis genome from gerBC (311 degrees) to licR (334
RT   degrees).";
RL   Microbiology 143:3313-3328(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   FUNCTION.
RC   STRAIN=168 / JH642, and 22a;
RX   PubMed=10572140; DOI=10.1128/jb.181.23.7346-7355.1999;
RA   Zheng G., Yan L.Z., Vederas J.C., Zuber P.;
RT   "Genes of the sbo-alb locus of Bacillus subtilis are required for
RT   production of the antilisterial bacteriocin subtilosin.";
RL   J. Bacteriol. 181:7346-7355(1999).
RN   [5]
RP   FUNCTION.
RC   STRAIN=168 / JH642;
RX   PubMed=10809709; DOI=10.1128/jb.182.11.3266-3273.2000;
RA   Zheng G., Hehn R., Zuber P.;
RT   "Mutational analysis of the sbo-alb locus of Bacillus subtilis:
RT   identification of genes required for subtilosin production and immunity.";
RL   J. Bacteriol. 182:3266-3273(2000).
RN   [6]
RP   TRANSCRIPTIONAL REGULATION.
RC   STRAIN=168 / JH642;
RX   PubMed=10809710; DOI=10.1128/jb.182.11.3274-3277.2000;
RA   Nakano M.M., Zheng G., Zuber P.;
RT   "Dual control of sbo-alb operon expression by the Spo0 and ResDE systems of
RT   signal transduction under anaerobic conditions in Bacillus subtilis.";
RL   J. Bacteriol. 182:3274-3277(2000).
CC   -!- FUNCTION: Involved in the production of the bacteriocin subtilosin.
CC       Required for maximal production and for optimal immunity to subtilosin.
CC       {ECO:0000269|PubMed:10572140, ECO:0000269|PubMed:10809709}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Transcription is highly induced by oxygen limitation and is
CC       under dual and independent control of Spo0A-AbrB and ResDE.
CC       {ECO:0000269|PubMed:10809710}.
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DR   EMBL; AJ430547; CAD23200.1; -; Genomic_DNA.
DR   EMBL; Z80360; CAB02508.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15765.1; -; Genomic_DNA.
DR   PIR; A70059; A70059.
DR   RefSeq; NP_391618.1; NC_000964.3.
DR   RefSeq; WP_003222006.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; P71010; -.
DR   SMR; P71010; -.
DR   STRING; 224308.BSU37380; -.
DR   PaxDb; P71010; -.
DR   EnsemblBacteria; CAB15765; CAB15765; BSU_37380.
DR   GeneID; 64305514; -.
DR   GeneID; 937057; -.
DR   KEGG; bsu:BSU37380; -.
DR   PATRIC; fig|224308.179.peg.4048; -.
DR   BioCyc; BSUB:BSU37380-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030152; P:bacteriocin biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0030153; P:bacteriocin immunity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Antibiotic biosynthesis; Bacteriocin biosynthesis; Bacteriocin immunity;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..53
FT                   /note="Antilisterial bacteriocin subtilosin biosynthesis
FT                   protein AlbB"
FT                   /id="PRO_0000064543"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   53 AA;  6116 MW;  CCE4BE818BB2D6E7 CRC64;
     MSPAQRRILL YILSFIFVIG AVVYFVKSDY LFTLIFIAIA ILFGMRARKA DSR