ID   FOS_MSVFB               Reviewed;         381 AA.
AC   P01102;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=p55-v-Fos-transforming protein;
GN   Name=V-FOS;
OS   FBJ murine osteosarcoma virus (FBJ-MSV) (Finkel-Biskis-Jinkins murine
OS   osteosarcoma virus).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Gammaretrovirus.
OX   NCBI_TaxID=11805;
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6301687; DOI=10.1016/0092-8674(83)90306-9;
RA   van Beveren C., van Straaten F., Curran T., Mueller R., Verma I.M.;
RT   "Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral
RT   and cellular fos gene products have different carboxy termini.";
RL   Cell 32:1241-1255(1983).
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bZIP family. Fos subfamily. {ECO:0000305}.
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DR   EMBL; V01184; CAA24505.1; -; Genomic_DNA.
DR   PIR; A01344; TVMVJ.
DR   SMR; P01102; -.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR000837; AP-1.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   InterPro; IPR029816; c-Fos/v-Fos.
DR   PANTHER; PTHR23351; PTHR23351; 1.
DR   PANTHER; PTHR23351:SF4; PTHR23351:SF4; 1.
DR   Pfam; PF00170; bZIP_1; 1.
DR   PRINTS; PR00042; LEUZIPPRFOS.
DR   SMART; SM00338; BRLZ; 1.
DR   SUPFAM; SSF57959; SSF57959; 1.
DR   PROSITE; PS50217; BZIP; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Host nucleus; Oncogene; Phosphoprotein.
FT   CHAIN           1..381
FT                   /note="p55-v-Fos-transforming protein"
FT                   /id="PRO_0000076460"
FT   DOMAIN          137..200
FT                   /note="bZIP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          139..159
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          165..193
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
SQ   SEQUENCE   381 AA;  41648 MW;  D15FFDB258949A9D CRC64;
     MMFSGFNADY EASSFRCSSA SPAGDSLSYY HSPADSFSSM GSPVNTQDFC ADLSVSSANF
     IPTVTATSTS PDLQWLVQPT LVSSVAPSQT RAPHPYGLPT QSAGAYARAE MVKTVSGGRA
     QSIGRRGKVE QLSPEEEEKR RIRRERNKMA AAKCRNRRRE LTDTLQAETD QLEDKKSALQ
     TEIANLLKEK EKLEFILAAH RPACKIPDDL GFPEEMSVAS LDLTGGLPEA STPESEEAFT
     LPLLNDPEPK PSLEPVKSIS NVELKAEPFD DFLFPASSRP SGSETSRSVP NVDLSGSFYA
     ADWEPLHSNS LGMGPMVTEL EPLCTPVVTC TPLLRLPELT HAAGPVSSQR RQGSRHPDVP
     LPELVHYREE KHVFPQRFPS T