ID   FOXA_SALTS              Reviewed;         702 AA.
AC   E1W8M5; Q56145;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Ferrioxamine B receptor;
DE   Flags: Precursor;
GN   Name=foxA; OrderedLocusNames=SL1344_0359;
OS   Salmonella typhimurium (strain SL1344).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=216597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL1344;
RX   PubMed=22538806; DOI=10.1073/pnas.1201061109;
RA   Kroger C., Dillon S.C., Cameron A.D., Papenfort K., Sivasankaran S.K.,
RA   Hokamp K., Chao Y., Sittka A., Hebrard M., Handler K., Colgan A.,
RA   Leekitcharoenphon P., Langridge G.C., Lohan A.J., Loftus B., Lucchini S.,
RA   Ussery D.W., Dorman C.J., Thomson N.R., Vogel J., Hinton J.C.;
RT   "The transcriptional landscape and small RNAs of Salmonella enterica
RT   serovar Typhimurium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:E1277-E1286(2012).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-374, AND FUNCTION.
RC   STRAIN=SL1344;
RX   PubMed=10103258; DOI=10.1128/aem.65.4.1610-1618.1999;
RA   Kingsley R.A., Reissbrodt R., Rabsch W., Ketley J.M., Tsolis R.M.,
RA   Everest P., Dougan G., Baeumler A.J., Roberts M., Williams P.H.;
RT   "Ferrioxamine-mediated iron(III) utilization by Salmonella enterica.";
RL   Appl. Environ. Microbiol. 65:1610-1618(1999).
CC   -!- FUNCTION: Ferrioxamine binding and uptake, in association with the TonB
CC       protein (By similarity). May play a role in intestinal colonization.
CC       {ECO:0000250, ECO:0000269|PubMed:10103258}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane.
CC   -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC       {ECO:0000305}.
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DR   EMBL; FQ312003; CBW16459.1; -; Genomic_DNA.
DR   EMBL; AF060876; AAC15464.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1W8M5; -.
DR   SMR; E1W8M5; -.
DR   EnsemblBacteria; CBW16459; CBW16459; SL1344_0359.
DR   KEGG; sey:SL1344_0359; -.
DR   PATRIC; fig|216597.6.peg.400; -.
DR   HOGENOM; CLU_008287_9_0_6; -.
DR   OMA; QVDPWFL; -.
DR   BioCyc; SENT216597:SL1344_RS01865-MON; -.
DR   Proteomes; UP000008962; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015344; F:siderophore uptake transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.130.10; -; 1.
DR   Gene3D; 2.40.170.20; -; 1.
DR   InterPro; IPR012910; Plug_dom.
DR   InterPro; IPR037066; Plug_dom_sf.
DR   InterPro; IPR039423; TonB-dep_rcpt.
DR   InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR   InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR   InterPro; IPR010105; TonB_sidphr_rcpt.
DR   PANTHER; PTHR32552; PTHR32552; 1.
DR   Pfam; PF07715; Plug; 1.
DR   Pfam; PF00593; TonB_dep_Rec; 1.
DR   TIGRFAMs; TIGR01783; TonB-siderophor; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Iron; Iron transport; Membrane;
KW   Receptor; Signal; TonB box; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..702
FT                   /note="Ferrioxamine B receptor"
FT                   /id="PRO_0000406084"
FT   CONFLICT        246..247
FT                   /note="MA -> SP (in Ref. 2; AAC15464)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        255
FT                   /note="G -> R (in Ref. 2; AAC15464)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        279
FT                   /note="F -> S (in Ref. 2; AAC15464)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        352
FT                   /note="A -> P (in Ref. 2; AAC15464)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        368..374
FT                   /note="HRLLVGI -> SSSAGGD (in Ref. 2; AAC15464)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   702 AA;  77702 MW;  FB2571D7CE2B8C63 CRC64;
     MPLEMFMFAT TRMALLIGGA IGGATFPLFA QETTKNDTVI VTSPVQSGAT KLATPDIETP
     QSVSIITRQQ FEEQGATSVR QAVSYTPGVY SNQIGASNRF DYIVLRGFSD GSLDNVYLDG
     LKMMGDTNSH SSLVVDPWFL EDIEVVRGPA SVLYGRSSPG GIVALTSRKP AFDAGGEVKL
     FAGNNNQRGA AFDVTGPLDD NERVAARLSG MTRYADSQFT PLKEERYALM PSLTWRITDR
     TRLDLMAYLH RDPEGGSHSG LPYQGTVVPY NGGKISNTFF EGEDDYDKYD RRENMVGYNI
     EHLFDNGWSV RQKLRYLHTK VTLNQVYAAG WLNETALNRG YSGSGEKMSA IALDNQLDGS
     VDTGAINHRL LVGIDYQDRS NHTTGYYGAF PPIDAFNPVY GAQPDYITLY SREKHKLRQT
     GYYLQDQMSW DRWRFTLGGR YDRVSVSNID KLHDSRSDLD KNNVSTRAAL LYLFDNGVAP
     YLSYSTAFTP TSFADENGNV LEPMKGKQWE AGVKYEPPGG NSQFSAAVYR INQTNIATKE
     EPTDPYRSIG EIESKGVELE AISHLSDSVR LQAAYTYTDI RYKKSSPQEQ GKRAVYAPRN
     QASAWLSYDV KSGLLEGLTL GSGIRYVNGV TSDRLNTHTL PSYTLVDMVV GYDLSSIGLN
     GLSAQLNVNN LTDKRYVAAC NSLSYCYFGA ERSIVGSVSW AF