ID   FOXA_YEREN              Reviewed;         710 AA.
AC   Q01674;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 2.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Ferrioxamine receptor;
DE   Flags: Precursor;
GN   Name=foxA;
OS   Yersinia enterocolitica.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 51872 / WA-C / Serotype O:8;
RX   PubMed=1640832; DOI=10.1111/j.1365-2958.1992.tb00852.x;
RA   Baeumler A.J., Hantke K.;
RT   "Ferrioxamine uptake in Yersinia enterocolitica: characterization of the
RT   receptor protein FoxA.";
RL   Mol. Microbiol. 6:1309-1321(1992).
RN   [2]
RP   SEQUENCE REVISION.
RA   Baeumler A.J.;
RL   Submitted (NOV-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Ferrioxamine binding and uptake, in association with the TonB
CC       protein.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC       {ECO:0000305}.
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DR   EMBL; X60447; CAA42975.1; -; Genomic_DNA.
DR   PIR; S22673; S22673.
DR   AlphaFoldDB; Q01674; -.
DR   SMR; Q01674; -.
DR   STRING; 1443113.LC20_04880; -.
DR   TCDB; 1.B.14.1.17; the outer membrane receptor (omr) family.
DR   eggNOG; COG4774; Bacteria.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015344; F:siderophore uptake transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.130.10; -; 1.
DR   Gene3D; 2.40.170.20; -; 1.
DR   InterPro; IPR012910; Plug_dom.
DR   InterPro; IPR037066; Plug_dom_sf.
DR   InterPro; IPR039423; TonB-dep_rcpt.
DR   InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR   InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR   InterPro; IPR010917; TonB_rcpt_CS.
DR   InterPro; IPR010105; TonB_sidphr_rcpt.
DR   PANTHER; PTHR32552; PTHR32552; 1.
DR   Pfam; PF07715; Plug; 1.
DR   Pfam; PF00593; TonB_dep_Rec; 1.
DR   TIGRFAMs; TIGR01783; TonB-siderophor; 1.
DR   PROSITE; PS00430; TONB_DEPENDENT_REC_1; 1.
DR   PROSITE; PS01156; TONB_DEPENDENT_REC_2; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Iron; Iron transport; Membrane;
KW   Receptor; Signal; TonB box; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..710
FT                   /note="Ferrioxamine receptor"
FT                   /id="PRO_0000034755"
FT   TRANSMEM        29..37
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..73
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..99
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..114
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..145
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..160
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..188
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..202
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        208..216
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        259..267
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..279
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..301
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        309..317
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..361
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        370..378
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        427..435
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        443..451
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        476..484
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        491..499
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        517..525
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        531..539
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        555..563
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        567..575
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        579..587
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        610..618
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        624..632
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        649..657
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        671..679
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        684..692
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        702..710
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   MOTIF           28..35
FT                   /note="TonB box"
FT   MOTIF           693..710
FT                   /note="TonB C-terminal box"
SQ   SEQUENCE   710 AA;  78383 MW;  82EB6EC1546900B8 CRC64;
     MFSAFIIKRS AILCSLAMFI PLASIADDTI EVTAKAGHEA DLPTSGYTAT TTKGATKTDQ
     PLILTAQSVS VVTRQQMDDQ NVATVNQALN YTPGVFTGFS GGATRYDTVA LRGFHGGDVN
     NTFLDGLRLL SDGGSYNVLQ VDPWFLERID VIKGPSSALY GQSIPGGVVM MTSKRPQFTS
     EGHFRLTAGN NNTQVAAFDY TDAISEHWAF RLTGITRNSD TMYDHQREER YAIAPSLLWQ
     PDENTSLLLR ANLQKDPSGG YHSAVPADGS IYGQKLSRGF FDGESNHNVF KRWQQIYSYE
     FSHKFDDVWS FRQNASYTHS NTQLEQVYQG GWNSDRTLMN RYYSGEDSSL NAFAVDNQLE
     ADLRTAAVKH KVLLGVDFQK FRNNLRSDSA YATPLNPYTG VSGGSTLYSD YLLTTPGINT
     SYLSRRYEQS GVYLQDEMTL DNWHLNLSGR YDRMKTENIN NTANSTDERT DNHASGRASL
     LYSFDSGISP YVSYSQAITP SLFPDAQQKL LKPMTSEQYE VGIIYQPPGS TSLYSAALYD
     LTQNDVANRA VPATYYVPAG KVNSQGLELE ARSQISDRLS VIAGYTYNRV KFKDAIDGND
     GNTPVLAPSN MASLWAQYEA GYGINVGAGI RYIGKQWADD ANTLRVPSYT LGDASVRADL
     GTWAASLKGA FVQLNVNNIA DKKYVAACYS TSYCYWGAER SVQATVGYDF