FOXNB_HUMAN
ID FOXNB_HUMAN Reviewed; 175 AA.
AC Q6ZUU3; A6NGX0;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=FOXL2 neighbor protein;
GN Name=FOXL2NB; Synonyms=C3orf72;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
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DR EMBL; AK125319; BAC86125.1; -; mRNA.
DR EMBL; AC092947; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS43155.1; -.
DR RefSeq; NP_001035150.1; NM_001040061.2.
DR AlphaFoldDB; Q6ZUU3; -.
DR BioGRID; 134915; 1.
DR STRING; 9606.ENSP00000372651; -.
DR iPTMnet; Q6ZUU3; -.
DR PhosphoSitePlus; Q6ZUU3; -.
DR BioMuta; FOXL2NB; -.
DR PaxDb; Q6ZUU3; -.
DR PeptideAtlas; Q6ZUU3; -.
DR PRIDE; Q6ZUU3; -.
DR ProteomicsDB; 68369; -.
DR Antibodypedia; 70523; 19 antibodies from 8 providers.
DR DNASU; 401089; -.
DR Ensembl; ENST00000383165.4; ENSP00000372651.3; ENSG00000206262.9.
DR GeneID; 401089; -.
DR KEGG; hsa:401089; -.
DR MANE-Select; ENST00000383165.4; ENSP00000372651.3; NM_001040061.3; NP_001035150.1.
DR UCSC; uc003esx.2; human.
DR CTD; 401089; -.
DR DisGeNET; 401089; -.
DR GeneCards; FOXL2NB; -.
DR HGNC; HGNC:34428; FOXL2NB.
DR HPA; ENSG00000206262; Tissue enhanced (ovary, parathyroid gland).
DR neXtProt; NX_Q6ZUU3; -.
DR OpenTargets; ENSG00000206262; -.
DR PharmGKB; PA162379723; -.
DR VEuPathDB; HostDB:ENSG00000206262; -.
DR eggNOG; ENOG502TEE5; Eukaryota.
DR GeneTree; ENSGT00410000029590; -.
DR HOGENOM; CLU_1532066_0_0_1; -.
DR InParanoid; Q6ZUU3; -.
DR OMA; ISLPKMC; -.
DR PhylomeDB; Q6ZUU3; -.
DR PathwayCommons; Q6ZUU3; -.
DR BioGRID-ORCS; 401089; 9 hits in 1059 CRISPR screens.
DR GenomeRNAi; 401089; -.
DR Pharos; Q6ZUU3; Tdark.
DR PRO; PR:Q6ZUU3; -.
DR Proteomes; UP000005640; Chromosome 3.
DR RNAct; Q6ZUU3; protein.
DR Bgee; ENSG00000206262; Expressed in left ovary and 53 other tissues.
DR ExpressionAtlas; Q6ZUU3; baseline and differential.
DR GO; GO:0001650; C:fibrillar center; IDA:HPA.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..175
FT /note="FOXL2 neighbor protein"
FT /id="PRO_0000348439"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 175 AA; 18625 MW; C2E88BF6BB95FEB9 CRC64;
MTRTPVGSAR TRPKPRKLGP QRGKALQASS RLSESPALVK KRMPDACTLG RAGIGLPKMC
LHMAVRHSKA QKTGPGILQQ RQKPPAPRAS GGPALLGKRR GCSEAGSASL EPLSSSRAAA
GCLNQVPLSP FLAGPRNTRR LPAPERERIE LAATLCLEGW PLRCLASKGK LHCVY
