ID   ALCS_ASPFC              Reviewed;         272 AA.
AC   B0YBR5;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 2.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Protein alcS {ECO:0000250|UniProtKB:Q460G9};
GN   Name=alcS {ECO:0000250|UniProtKB:Q460G9}; ORFNames=AFUB_087570;
OS   Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus
OS   fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=451804;
RN   [1] {ECO:0000312|EMBL:EDP48046.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CEA10 / CBS 144.89 / FGSC A1163;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cell
CC       septum {ECO:0000250|UniProtKB:Q460G9, ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the acetate uptake transporter (AceTr) (TC
CC       2.A.96) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDP48046.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS499601; EDP48046.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; B0YBR5; -.
DR   SMR; B0YBR5; -.
DR   PRIDE; B0YBR5; -.
DR   PhylomeDB; B0YBR5; -.
DR   Proteomes; UP000001699; Unassembled WGS sequence.
DR   GO; GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR030186; AlcS/PatA.
DR   InterPro; IPR000791; Gpr1/Fun34/SatP.
DR   PANTHER; PTHR31123:SF4; PTHR31123:SF4; 1.
DR   Pfam; PF01184; Gpr1_Fun34_YaaH; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..272
FT                   /note="Protein alcS"
FT                   /id="PRO_0000393861"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   272 AA;  29038 MW;  2F852706A0DC3B66 CRC64;
     MDTEQGLKNH TAKTSPHDET AMASLTTIPT SVTLSAEQFE KLYLSPLTQR QGMLSKQMGN
     PTPLALGGFV ITTTPLSCCL MGWRGATGSG IAFTGPIIFL GGGLLVLTSI LEFILGNTFP
     CVVFGTIGAF WFAFGCTMTP AFNAAAPFST SATDTVAGLS SPDFLNTYAF LFIWMGVLML
     IFLACATRTN AVYVAIFTTL TLVFGFLSGA YWRLAVADAL VGNRLVVAAG ACLFVASMLG
     FYLLVAQLFD SVGLPVRLPV GDLSRFWDRR AR