FPP2_ARATH
ID FPP2_ARATH Reviewed; 629 AA.
AC Q9SFF4; F4HZP6; Q0WRM5; Q84WK7; Q9XHZ6;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Filament-like plant protein 2 {ECO:0000303|PubMed:11972898};
DE Short=AtFPP2 {ECO:0000303|PubMed:11972898};
DE AltName: Full=Protein VESICLE TETHERING 2 {ECO:0000303|PubMed:25541219};
GN Name=FPP2 {ECO:0000303|PubMed:11972898};
GN Synonyms=VETH2 {ECO:0000303|PubMed:25541219};
GN OrderedLocusNames=At1g21810 {ECO:0000312|Araport:AT1G21810};
GN ORFNames=F8K7.24 {ECO:0000312|EMBL:AAD41435.1},
GN T26F17.2 {ECO:0000312|EMBL:AAF16547.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 405-629.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 429-629.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11972898; DOI=10.1186/1471-2164-3-9;
RA Gindullis F., Rose A., Patel S., Meier I.;
RT "Four signature motifs define the first class of structurally related large
RT coiled-coil proteins in plants.";
RL BMC Genomics 3:9-9(2002).
RN [6]
RP FUNCTION, INTERACTION WITH COG2, TISSUE SPECIFICITY, AND SUBCELLULAR
RP LOCATION.
RX PubMed=25541219; DOI=10.1093/pcp/pcu197;
RA Oda Y., Iida Y., Nagashima Y., Sugiyama Y., Fukuda H.;
RT "Novel coiled-coil proteins regulate exocyst association with cortical
RT microtubules in xylem cells via the conserved oligomeric golgi-complex 2
RT protein.";
RL Plant Cell Physiol. 56:277-286(2015).
CC -!- FUNCTION: Ensures, when in complex with FPP3/VETH1 and COG2, the
CC correct secondary cell wall (SCW) deposition pattern by recruiting
CC exocyst components to cortical microtubules in xylem cells during
CC secondary cell wall deposition by recruiting EXO70A1.
CC {ECO:0000269|PubMed:25541219}.
CC -!- SUBUNIT: Interacts with WPP/MAF proteins (By similarity). Binds to
CC COG2; this interaction promotes the association between cortical
CC microtubules and EXO70A1 (PubMed:25541219). {ECO:0000250,
CC ECO:0000269|PubMed:25541219}.
CC -!- SUBCELLULAR LOCATION: Vesicle {ECO:0000269|PubMed:25541219}.
CC Note=Present in vesicle-like small compartments which exhibit
CC microtubule plus-end-directed and end-tracking dynamics.
CC {ECO:0000269|PubMed:25541219}.
CC -!- TISSUE SPECIFICITY: Accumulates in preferentially xylem cells.
CC {ECO:0000269|PubMed:25541219}.
CC -!- SIMILARITY: Belongs to the FPP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD41435.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007727; AAD41435.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC013482; AAF16547.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30158.2; -; Genomic_DNA.
DR EMBL; CP002684; ANM58512.1; -; Genomic_DNA.
DR EMBL; AK228278; BAF00224.1; -; mRNA.
DR EMBL; BT003117; AAO24549.1; -; mRNA.
DR PIR; F86351; F86351.
DR RefSeq; NP_001320941.1; NM_001332529.1.
DR RefSeq; NP_173599.2; NM_102029.3.
DR AlphaFoldDB; Q9SFF4; -.
DR SMR; Q9SFF4; -.
DR BioGRID; 24023; 2.
DR IntAct; Q9SFF4; 2.
DR STRING; 3702.AT1G21810.1; -.
DR PaxDb; Q9SFF4; -.
DR PRIDE; Q9SFF4; -.
DR ProteomicsDB; 230112; -.
DR EnsemblPlants; AT1G21810.1; AT1G21810.1; AT1G21810.
DR EnsemblPlants; AT1G21810.3; AT1G21810.3; AT1G21810.
DR GeneID; 838784; -.
DR Gramene; AT1G21810.1; AT1G21810.1; AT1G21810.
DR Gramene; AT1G21810.3; AT1G21810.3; AT1G21810.
DR KEGG; ath:AT1G21810; -.
DR Araport; AT1G21810; -.
DR eggNOG; ENOG502QQJ4; Eukaryota.
DR HOGENOM; CLU_012828_0_0_1; -.
DR InParanoid; Q9SFF4; -.
DR OMA; YFKLAME; -.
DR OrthoDB; 190231at2759; -.
DR PhylomeDB; Q9SFF4; -.
DR PRO; PR:Q9SFF4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SFF4; baseline and differential.
DR Genevisible; Q9SFF4; AT.
DR GO; GO:0031410; C:cytoplasmic vesicle; IDA:UniProtKB.
DR GO; GO:0060178; P:regulation of exocyst localization; IDA:UniProtKB.
DR InterPro; IPR008587; FPP_plant.
DR Pfam; PF05911; FPP; 4.
PE 1: Evidence at protein level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..629
FT /note="Filament-like plant protein 2"
FT /id="PRO_0000347200"
FT REGION 186..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 34..61
FT /evidence="ECO:0000255"
FT COILED 102..171
FT /evidence="ECO:0000255"
FT COILED 270..493
FT /evidence="ECO:0000255"
SQ SEQUENCE 629 AA; 71106 MW; AB03C32EE40A0D94 CRC64;
MMTGTTLILE PVMDSKDELV KQHAKVAEDA VAGWEKAENE VVELKQKLED AADKNIVLED
RVSHLDGALK ECVRQLRQFR DEQEKNIQAA VTESTKELHS ANTGLEKRVL ELQKEAEAAK
SENMMLRREF LTQREDLEIV MIERDLSTQA AETASKQHLD IIKKLAKLEA ECRKLRILAK
TSSSLSSNQS VDSHSDGGRE RVEGSCSDSW ASSAFISELD QIKNEKGGNR SLQGTTSSTE
IDLMDDFLEM ERLVALPTET QAKNSKDGYE LSLMEKLEKI QAEKDDLERE VKCCREAEKR
LSLEIEAVVG DKMELEDMLK RVEAEKAELK TSFDVLKDKY QESRVCFQEV DTKLEKLQAE
KDELDSEVIC CKEAEKRFSL ELEAVVGDKI EMEDELEKME AEKAELKISF DVIKDQYQES
RVCFQEVEMK LEAMKRELKL ANESKTQAES RVTRMEAEVR KERIVSDGLK EKCETFEEEL
RREIEEKTMI KREKVEPKIK QEDIATAAGK FADCQKTIAS LGKQLQSLAT LEEFLIDTAS
IPGSARSVHN KEALLGKDPH ECIKTINGRS LEFLAIQNSN NKTSPPCSSS SDSTTVSLIM
SSNRGSSEKN RNGFATVFTR SRNSVNLGI
