FR8P1_HUMAN
ID FR8P1_HUMAN Reviewed; 369 AA.
AC Q9BZ68; A1A4X4;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-NOV-2009, sequence version 2.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Putative FERM domain-containing protein FRMD8P1;
DE AltName: Full=FERM domain-containing 8 pseudogene 1;
GN Name=FRMD8P1; ORFNames=FKSG43;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Wang Y.-G., Gong L.;
RT "Cloning and characterization of FKSG43, a novel gene located on human
RT chromosome Xq12.1-13.";
RL Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- CAUTION: Could be the product of a pseudogene. Related to FRMD8.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG50294.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF334945; AAG50294.1; ALT_SEQ; mRNA.
DR EMBL; BC128150; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q9BZ68; -.
DR SMR; Q9BZ68; -.
DR IntAct; Q9BZ68; 1.
DR BioMuta; HGNC:24690; -.
DR DMDM; 269849595; -.
DR jPOST; Q9BZ68; -.
DR MassIVE; Q9BZ68; -.
DR MaxQB; Q9BZ68; -.
DR PeptideAtlas; Q9BZ68; -.
DR PRIDE; Q9BZ68; -.
DR GeneCards; FRMD8P1; -.
DR HGNC; HGNC:24690; FRMD8P1.
DR neXtProt; NX_Q9BZ68; -.
DR InParanoid; Q9BZ68; -.
DR PathwayCommons; Q9BZ68; -.
DR SignaLink; Q9BZ68; -.
DR Pharos; Q9BZ68; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q9BZ68; protein.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:GO_Central.
DR CDD; cd14473; FERM_B-lobe; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR Pfam; PF00373; FERM_M; 1.
DR SUPFAM; SSF47031; SSF47031; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..369
FT /note="Putative FERM domain-containing protein FRMD8P1"
FT /id="PRO_0000295777"
FT DOMAIN 30..369
FT /note="FERM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00084"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 41136 MW; 4E38687E625F3AD2 CRC64;
MDGTEGSVGQ PGPTERSHRS SVSSVGARAA DVLVYLADDT VVPLAVENLP SLRAHELHCA
VREVLKLPDI ALDVFALWLV SPLLEVQLKP KNQPYKLGRQ WPELLLRFTS APDDDVAMDE
PFLQFRRNVF FPKGRELQIP DEEVLRLLYE EAKGNVLAAR YLCDVEDCEA LGALVCRVQL
VTYQPDWPAA CDLREKLDSF LPAHLCKRGQ GLFAALRGRG ARAGPGEQSL LNAYRKVQEV
SSDGGCEAAL GTHYRAYLLK CHKLPFYGCA FFHGEVDKPA QGFLHRGGRK SVSVAISLEG
VHVVDSREKH VLLGLCFQEL SWDHTSPEEE EPILWLEFDR DSGVTPVNKL LKIYSKQAEL
MSSLIEYCI