ID   FRA1D_FRAAN             Reviewed;         160 AA.
AC   Q256S6;
DT   08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Major strawberry allergen Fra a 1-D {ECO:0000303|PubMed:16945416};
DE   AltName: Full=Fra a 1.01D {ECO:0000305};
DE   AltName: Allergen=Fra a 1 {ECO:0000305};
GN   Name=FRAA1D {ECO:0000303|PubMed:16945416};
OS   Fragaria ananassa (Strawberry) (Fragaria chiloensis x Fragaria virginiana).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae;
OC   Fragaria.
OX   NCBI_TaxID=3747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Leaf;
RX   PubMed=16945416; DOI=10.1016/j.molimm.2006.06.004;
RA   Musidlowska-Persson A., Alm R., Emanuelsson C.;
RT   "Cloning and sequencing of the Bet v 1-homologous allergen Fra a 1 in
RT   strawberry (Fragaria ananassa) shows the presence of an intron and little
RT   variability in amino acid sequence.";
RL   Mol. Immunol. 44:1245-1252(2007).
CC   -!- SUBUNIT: Monomer. {ECO:0000250|UniProtKB:Q256S2}.
CC   -!- ALLERGEN: May cause an allergic reaction in human (By similarity).
CC       Binds to IgE of patients allergic to strawberry (By similarity).
CC       {ECO:0000250|UniProtKB:Q5ULZ4}.
CC   -!- SIMILARITY: Belongs to the BetVI family. {ECO:0000305}.
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DR   EMBL; AM236316; CAJ85642.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q256S6; -.
DR   SMR; Q256S6; -.
DR   Allergome; 2124; Fra a 1.
DR   GO; GO:0010427; F:abscisic acid binding; IEA:InterPro.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR000916; Bet_v_I/MLP.
DR   InterPro; IPR024949; Bet_v_I_allergen.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   Pfam; PF00407; Bet_v_1; 1.
DR   PRINTS; PR00634; BETALLERGEN.
PE   3: Inferred from homology;
KW   Allergen; Pathogenesis-related protein; Plant defense.
FT   CHAIN           1..160
FT                   /note="Major strawberry allergen Fra a 1-D"
FT                   /id="PRO_0000447011"
SQ   SEQUENCE   160 AA;  17770 MW;  6176FC16CD54B41E CRC64;
     MGGYTYENEF TSDIPAPKLF KAFVLDADNL IPKIAPQAIK CAEILEGDGG PGTIKKITFG
     EGSHYGYVKH KIHSIDKENH TYSYSLIEGD ALSDNIEKID YETKLVSAPH GGTIIKTTSK
     YHTKGDVEIK EEHVKAGKEK ASHLFKLIEG YLKDHPSEYN